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. Author manuscript; available in PMC: 2019 Apr 17.
Published in final edited form as: Neuroimage. 2017 Jul 3;157:233–249. doi: 10.1016/j.neuroimage.2017.06.009

Table 3 -.

Intra-rater mean Dice Kappa, range of WMHLs, and number (N) of subjects with low (<5cm3), medium (5–20cm3), and high (>20cm3) WMHLs for manual segmentations of WMHs in different datasets. WMHL= White Matter Hyperintensity Load.

Dataset ADC NACC ADNI1 ADNI2/GO
Dice Kappa 0.72 0.78 0.80 0.86
WMHL Range (cm3) 0.2–148.6 0.2–109.0 0.0–119.3 0.2–63.0
NWMHL<5cm3 36 6 14 16
N5cm3<WMHL<20cm3 23 11 10 11
NWMHL<20cm3 11 12 27 18