Table 1.

In Vitro Potency and Efficacy Data of Amide and Triazole-Containing Correctors in the VX-809 Chemical Series in F508del CFBE41o-Cells.

compd	EC50 (μM)[a]	Maximal Response[b]
11	0.660 ± 0.287	48.1%
20	inactive	--
23	1.960 ± 0.754	120.1%
26	2.971 ± 0.900	54.1%
33	0.427 ± 0.514	49.9%

^[a]Mean and standard deviation values from at least three determinations are reported.

^[b]Maximal response is reported as % activity of the 3 μM VX-809 response.