Table 5. Susceptibility of deletion strains to antifungal treatments*.
| Strain | 1mM H2O2 | 150 µg/ml CFW | 75 ng/ml CSP | 0.75 μg/ml AMPB |
|---|---|---|---|---|
| wsc1∆ | S | S | S | Wt |
| mid2∆ | S | Wt | S | Wt |
| abp1Δ | Wt | Wt | Wt | Wt |
| atx1Δ | S | Wt | S | Wt |
| bgl2Δ | Wt | Wt | Wt | Wt |
| crn1Δ | Wt | Wt | Wt | Wt |
| egd1Δ | Wt | Wt | Wt | Wt |
| egd2Δ | Wt | Wt | Wt | Wt |
| fpr1Δ | Wt | Wt | Wt | Wt |
| grx1Δ | S | Wt | S | Wt |
| gtt1Δ | Wt | Wt | Wt | Wt |
| msh6Δ | Wt | Wt | Wt | Wt |
| mek1∆ | Wt | Wt | Wt | Wt |
| par32Δ | Wt | Wt | Wt | Wt |
| pdc1Δ | Wt | Wt | Wt | Wt |
| pst2Δ | Wt | Wt | Wt | Wt |
| ras2Δ | S | Wt | Wt | Wt |
| rpl24aΔ | Wt | Wt | Wt | Wt |
| rpl40aΔ | Wt | Wt | S | Wt |
| rps0bΔ | Wt | Wt | Wt | Wt |
| sgt2Δ | Wt | Wt | Wt | Wt |
| ssb1Δ | Wt | Wt | S | Wt |
| sso2Δ | Wt | Wt | Wt | Wt |
| yck1Δ | Wt | Wt | Wt | Wt |
| ypl199cΔ | Wt | Wt | Wt | Wt |
| zeo1Δ | Wt | Wt | Wt | Wt |
| atx1Δmid2Δ | S | — | S | — |
| grx1Δmid2Δ | S | — | S | — |
| ras2Δmid2Δ | S | — | S | — |
| ras2Δwsc1Δ | S | — | S | — |
| zeo1Δmid2Δ | — | — | Wt | — |
| zeo1Δwsc1Δ | — | — | S | — |
cof1Δ, fas1Δ, fba1Δ, mtr3Δ, pga3Δ, rps31Δ, and ypl238cΔ strains were not tested because are nonviable. The strains lnp1Δ, ssb2Δ, and tef1Δ were not available in this study. H2O2 = Hydrogen Peroxide; CFW = Calcofluor White; CSP = Caspofungin; AMPB = Amphotericin B; Wt = growth equivalent to wild type; S = sensitive or growth two dilutions less than wild type; - = not tested.
*
A representative drop dilution assay is shown in Figure S10.