Table 2. Linear and mixed effect model results for pre- and post-perturbation selection coefficients for D. simulans mtDNA cage types. Selection coefficients for each cage (S cage) and the overall haplotype selection coefficient (S Haplotype) are shown. 95% confidence intervals are shown, along with the repeatability (VR) of the rank order of each cage within haplotype (see Materials and Methods). P-values (in parentheses) are from Chi-sq distributions. Bold denotes significance at α=0.05.
| Pre perturbation | Post perturbation | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| nDNA | Haplotype | Cage | S cage | S Haplotype | 95% CI | VR | S cage | S Haplotype | 95% CI | VR |
| OreR | mau12(siIII) | 1 | −0.161 (0.057) | −0.106 (0.025) | −0.156 to −0.056 | <0.001 | 0.037 (0.030) | −0.085 (0.040) | −0.185 to 0.009 | 0.37 |
| 2 | −0.155 (0.016) | (P = 1.0) | −0.242 (0.050) | (P = 0.28) | ||||||
| 3 | −0.024 (0.022) | −0.096 (0.007) | ||||||||
| 4 | −0.085 (0.075) | −0.039 (0.016) | ||||||||
| siI (siI) | 1 | 0.058 (0.019) | 0.062 (0.010) | 0.042 to 0.084 | 0.29 | −0.003 (0.001) | −0.000 (0.018) | −0.055 to 0.051 | 0.64 | |
| 2 | 0.079 (0.022) | (P = 0.11) | 0.063 (0.027) | (P = 0.04) | ||||||
| 3 | 0.037 (0.018) | −0.004 (0.033) | ||||||||
| 4 | 0.074 (0.021) | −0.057 (0.002) | ||||||||
| sm21(siII) | 1 | 0.030 (0.046) | −0.044 (0.020) | −0.085 to −0.0004 | 0.28 | −0.008 (0.009) | 0.025 (0.037) | −0.053 to 0.105 | <0.001 | |
| 2 | −0.109 (0.035) | (P = 0.11) | −0.089 (0.044) | (P = 0.85) | ||||||
| 3 | −0.031 (0.014) | 0.136 (0.077) | ||||||||
| 4 | −0.068 (0.034) | 0.062 (0.022) | ||||||||
| Aut | mau12(siIII) | 1 | 0.017 (0.034) | 0.013 (0.019) | −0.026 to 0.052 | <0.001 | 0.023 (0.010) | 0.017 (0.019) | −0.033 to 0.066 | 0.39 |
| 2 | 0.043 (0.052) | (P = 1.0) | 0.006 (0.084) | (P = 0.25) | ||||||
| 3 | 0.041 (0.034) | 0.001 (0.026) | ||||||||
| 4 | −0.050 (0.029) | 0.039 (0.043) | ||||||||
| siI (siI) | 1 | −0.037 (0.030) | −0.029 (0.018) | −0.064 to 0.009 | <0.001 | −0.179 (0.013) | −0.083 (0.024) | −0.143 to −0.018 | 0.48 | |
| 2 | −0.024 (0.030) | (P = 0.72) | −0.048 (0.025) | (P = 0.15) | ||||||
| 3 | −0.074 (0.051) | −0.049 (0.014) | ||||||||
| 4 | 0.019 (0.014) | −0.055 (0.048) | ||||||||
| sm21(siII) | 1 | 0.064 (0.118) | 0.022 (0.034) | −0.051 to 0.090 | 0.10 | 0.037 (0.006) | 0.033 (0.010) | 0.013 to 0.054 | <0.001 | |
| 2 | −0.020 (0.070) | (P = 0.55) | 0.031 (0.021) | (P = 0.84) | ||||||
| 3 | 0.031 (0.046) | 0.050 (0.037) | ||||||||
| 4 | 0.014 (0.025) | 0.015 (0.004) | ||||||||