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. Author manuscript; available in PMC: 2020 Feb 28.
Published in final edited form as: Am J Nephrol. 2019 Feb 28;49(4):263–270. doi: 10.1159/000497445

Table 3.

Hazard ratios (95% CI) for all-cause mortality

FGF23
Trajectory
Low
Stable
Low
Increasing
Elevated
Increasing
Elevated
Decreasing
Elevated
Stable
Deaths
N (%)
67 (38) 64 (43) 92 (34) 43 (39) 75 (33)
Models and Analysis
Unadjusted 1.04
(0.75-1.45)
0.97
(0.69-1.36)
0.93
(0.68-1.26)
1.21
(0.83-1.77)
Reference
Model 1: age, race, sex 0.73
(0.52-1.04)
0.77
(0.54-1.09)
0.78
(0.57-1.07)
0.96
(0.65-1.41)
Reference
Model 2: model 1 + diabetes, cardiovascular disease, years on dialysis, Kt/V and Flux randomization arms, AV access, serum albumin 0.65
(0.45-0.92)
0.70
(0.49-1.00)
0.73
(0.54-1.02)
0.87
(0.59-1.29)
Reference
Model 3: model 2 + calcium, phosphorus, PTH, 25(OH)D, 1,25(OH)2D, and inflammatory markers 0.62
(0.42-0.92)
0.71
(0.48-1.03)
0.75
(0.55-1.05)
0.83
(0.55-1.24)
Reference
Model 4: model 3 + baseline vitamin D analog use 0.61
(0.41-0.92)
0.70
(0.48-1.03)
0.75
(0.54-1.04)
0.83
(0.55-1.23)
Reference
Model 5: model 4 + residual kidney function 0.61
(0.41-0.91)
0.70
(0.48-1.03)
0.75
(0.54-1.04)
0.82
(0.55-1.23)
Reference