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. 2009 Jun 1;12(3):542–551. doi: 10.1089/jmf.2008.1073

FIG. 1.

FIG. 1.

Effect of AMS on AAPH-induced (A) ROS generation and (B) GSH depletion in HEK293T cells. Cells were preincubated with or without AMS (1 μM or 5 μM) or N-acetylcysteine (NAC) (200 μM) for 6 hours prior to AAPH treatment. ROS and GSH levels were measured 1 hour after AAPH treatment. Three independent experiments were performed with quintuple assays. Results of one-factor ANOVA followed by Fisher's protected LSD post hoc test were used: **P < .01, ***P < .001 versus untreated control; ##P < .01, ###P < .001 versus AAPH-treated cells, respectively.