| Remission established: odds ratios, risk ratios and risk difference for all treatment comparisons ‐ random‐effects model | ||||
| Treatment | Reference | OR (95% CrI) | RR (95% CrI) | RD % (95% CrI) |
| MTX + DMARD | MTX + PL | 0.70(0.22,2.23) | 0.71(0.22,2.11) | ‐0.01(‐0.04,0.05) |
| PL | 1.02(0.12,8.51) | 1.02(0.13,6.35) | 0.00(‐0.05,0.25) | |
| SD ETN SC | 1.79(0.76,4.33) | 1.73(0.77,3.73) | 0.04(‐0.01,0.13) | |
| SD ADA SC | 1.22(0.20,8.20) | 1.21(0.21,6.15) | 0.01(‐0.04,0.24) | |
| SD GOLI IV | 1.42(0.41,5.02) | 1.39(0.42,4.22) | 0.02(‐0.03,0.15) | |
| SD GOLI SC | 3.62(0.36,35.55) | 3.21(0.38,13.57) | 0.11(‐0.03,0.59) | |
| SD ETN SC + MTX | 3.21(1.48,7.01) | 2.89(1.44,5.42) | 0.09(0.02,0.22) | |
| SD ABA IV + MTX | 4.73(2.39,9.83) | 3.99(2.23,6.95) | 0.15(0.06,0.28) | |
| SD ABA SC + MTX | 3.50(1.34,8.74) | 3.12(1.32,6.43) | 0.10(0.02,0.26) | |
| SD GOLI SC + MTX | 10.54(3.79,32.51) | 7.16(3.30,13.55) | 0.30(0.12,0.56) | |
| SD ADA SC + MTX | 3.94(1.73,9.61) | 3.44(1.67,6.81) | 0.12(0.03,0.28) | |
| SD INF IV + MTX | 2.26(0.88,6.08) | 2.13(0.88,4.89) | 0.06(‐0.01,0.19) | |
| SD RITUX IV + MTX | 3.63(1.35,10.50) | 3.21(1.33,7.25) | 0.11(0.02,0.30) | |
| SD GOLI IV + MTX | 3.27(1.24,8.88) | 2.94(1.22,6.48) | 0.09(0.01,0.26) | |
| SD CERTO + MTX | 10.74(1.18,283.80) | 7.24(1.17,21.74) | 0.31(0.01,0.88) | |
| SD TOFA PO + MTX | 4.30(0.91,25.42) | 3.69(0.92,11.98) | 0.13(0.00,0.51) | |
| LD GOLI IV | 2.21(0.65,7.72) | 2.09(0.66,5.86) | 0.05(‐0.02,0.23) | |
| LD RITUX IV + MTX | 1.51(0.58,4.16) | 1.48(0.59,3.61) | 0.02(‐0.02,0.13) | |
| LD ETN SC + MTX | 2.96(1.03,8.69) | 2.70(1.03,6.35) | 0.08(0.00,0.26) | |
| LD GOLI IV + MTX | 1.31(0.37,4.63) | 1.29(0.38,3.96) | 0.01(‐0.03,0.14) | |
| HD TOCI IV | 7.03(1.84,31.06) | 5.42(1.76,13.25) | 0.22(0.04,0.55) | |
| HD GOLI SC | 4.69(1.16,20.27) | 3.97(1.15,10.81) | 0.15(0.01,0.45) | |
| HD TOCI IV + MTX | 12.92(4.14,49.77) | 8.11(3.56,15.88) | 0.35(0.13,0.66) | |
| HD GOLI SC + MTX | 9.48(3.37,28.37) | 6.67(2.99,12.84) | 0.28(0.10,0.53) | |
| HD INF IV + MTX | 3.49(1.22,10.51) | 3.11(1.21,7.20) | 0.10(0.01,0.30) | |
| HD TOFA PO + MTX | 10.91(2.39,64.71) | 7.33(2.23,16.48) | 0.31(0.06,0.71) | |
| PL | MTX + DMARD | 1.45(0.13,16.52) | 1.42(0.14,12.42) | 0.01(‐0.07,0.26) |
| SD ETN SC | 2.56(0.89,7.68) | 2.42(0.89,6.93) | 0.05(‐0.01,0.13) | |
| SD ADA SC | 1.76(0.21,16.15) | 1.71(0.22,12.41) | 0.02(‐0.06,0.25) | |
| SD GOLI IV | 2.04(0.37,11.34) | 1.96(0.40,9.70) | 0.03(‐0.05,0.17) | |
| SD GOLI SC | 5.22(0.39,68.59) | 4.45(0.40,30.13) | 0.12(‐0.04,0.61) | |
| SD ETN SC + MTX | 4.56(1.89,11.45) | 4.02(1.76,9.98) | 0.10(0.04,0.20) | |
| SD ABA IV + MTX | 6.74(1.80,27.16) | 5.57(1.67,20.56) | 0.16(0.05,0.30) | |
| SD ABA SC + MTX | 4.96(1.09,22.38) | 4.33(1.08,17.14) | 0.11(0.01,0.28) | |
| SD GOLI SC + MTX | 15.31(3.22,75.02) | 10.02(2.67,37.41) | 0.31(0.12,0.57) | |
| SD ADA SC + MTX | 5.62(1.39,25.28) | 4.81(1.35,18.90) | 0.13(0.03,0.29) | |
| SD INF IV + MTX | 3.25(0.73,15.40) | 2.99(0.75,12.72) | 0.07(‐0.02,0.20) | |
| SD RITUX IV + MTX | 5.18(1.15,25.60) | 4.48(1.13,19.01) | 0.12(0.01,0.31) | |
| SD GOLI IV + MTX | 4.67(1.04,22.15) | 4.11(1.04,16.92) | 0.11(0.00,0.28) | |
| SD CERTO + MTX | 15.62(1.25,484.40) | 9.93(1.23,54.76) | 0.32(0.01,0.89) | |
| SD TOFA PO + MTX | 6.20(0.89,51.49) | 5.14(0.90,27.65) | 0.14(‐0.01,0.52) | |
| LD GOLI IV | 3.16(0.59,17.69) | 2.92(0.61,13.92) | 0.06(‐0.03,0.25) | |
| LD RITUX IV + MTX | 2.15(0.48,10.46) | 2.06(0.50,9.20) | 0.04(‐0.04,0.14) | |
| LD ETN SC + MTX | 4.24(1.07,17.46) | 3.78(1.07,13.63) | 0.09(0.00,0.26) | |
| LD GOLI IV + MTX | 1.87(0.34,10.69) | 1.81(0.36,9.21) | 0.03(‐0.05,0.15) | |
| HD TOCI IV | 10.18(1.72,66.28) | 7.53(1.62,32.99) | 0.23(0.04,0.56) | |
| HD GOLI SC | 6.78(1.08,43.15) | 5.55(1.07,25.91) | 0.16(0.01,0.46) | |
| HD TOCI IV + MTX | 18.61(3.66,112.50) | 11.21(2.96,44.17) | 0.36(0.13,0.67) | |
| HD GOLI SC + MTX | 13.61(2.86,68.76) | 9.29(2.45,35.46) | 0.29(0.10,0.54) | |
| HD INF IV + MTX | 4.98(1.07,25.53) | 4.33(1.06,18.66) | 0.11(0.00,0.31) | |
| HD TOFA PO + MTX | 15.72(2.31,130.70) | 10.00(2.09,43.78) | 0.32(0.06,0.72) | |
| SD ETN SC | PL | 1.76(0.18,17.32) | 1.69(0.24,15.33) | 0.03(‐0.21,0.14) |
| SD ADA SC | 1.21(0.07,20.18) | 1.20(0.09,16.14) | 0.01(‐0.23,0.23) | |
| SD GOLI IV | 1.41(0.12,16.35) | 1.38(0.15,14.33) | 0.02(‐0.23,0.16) | |
| SD GOLI SC | 3.52(0.81,16.88) | 2.95(0.83,11.43) | 0.09(‐0.01,0.45) | |
| SD ETN SC + MTX | 3.14(0.34,30.37) | 2.82(0.41,24.64) | 0.08(‐0.16,0.23) | |
| SD ABA IV + MTX | 4.66(0.50,44.57) | 3.92(0.58,34.30) | 0.14(‐0.12,0.29) | |
| SD ABA SC + MTX | 3.40(0.34,34.84) | 3.01(0.42,27.46) | 0.09(‐0.15,0.27) | |
| SD GOLI SC + MTX | 10.48(1.43,79.41) | 6.91(1.28,49.53) | 0.29(0.06,0.52) | |
| SD ADA SC + MTX | 3.92(0.40,39.59) | 3.40(0.47,30.44) | 0.11(‐0.14,0.29) | |
| SD INF IV + MTX | 2.25(0.22,23.79) | 2.11(0.28,19.89) | 0.05(‐0.20,0.19) | |
| SD RITUX IV + MTX | 3.60(0.34,38.36) | 3.15(0.42,29.24) | 0.10(‐0.15,0.30) | |
| SD GOLI IV + MTX | 3.21(0.31,33.38) | 2.87(0.39,26.31) | 0.09(‐0.16,0.27) | |
| SD CERTO + MTX | 11.15(0.48,564.20) | 6.80(0.54,81.10) | 0.29(‐0.09,0.88) | |
| SD TOFA PO + MTX | 4.29(0.30,70.57) | 3.60(0.36,41.14) | 0.12(‐0.15,0.50) | |
| LD GOLI IV | 2.17(0.18,25.75) | 2.04(0.23,20.97) | 0.05(‐0.20,0.23) | |
| LD RITUX IV + MTX | 1.49(0.15,16.00) | 1.45(0.19,14.02) | 0.02(‐0.22,0.14) | |
| LD ETN SC + MTX | 2.92(0.27,31.42) | 2.64(0.33,24.82) | 0.08(‐0.17,0.26) | |
| LD GOLI IV + MTX | 1.29(0.11,15.14) | 1.27(0.14,13.32) | 0.01(‐0.23,0.15) | |
| HD TOCI IV | 7.04(0.55,89.56) | 5.25(0.62,50.27) | 0.20(‐0.09,0.54) | |
| HD GOLI SC | 4.55(1.02,24.12) | 3.76(1.01,19.15) | 0.13(0.00,0.35) | |
| HD TOCI IV + MTX | 12.86(1.15,155.00) | 7.82(1.11,70.11) | 0.33(0.03,0.66) | |
| HD GOLI SC + MTX | 9.38(1.32,73.10) | 6.43(1.21,45.84) | 0.26(0.05,0.50) | |
| HD INF IV + MTX | 3.46(0.32,37.71) | 3.04(0.39,28.79) | 0.09(‐0.16,0.30) | |
| HD TOFA PO + MTX | 10.89(0.78,168.40) | 6.93(0.82,67.45) | 0.29(‐0.04,0.70) | |
| SD ADA SC | SD ETN SC | 0.69(0.09,5.40) | 0.71(0.10,4.25) | ‐0.02(‐0.14,0.20) |
| SD GOLI IV | 0.80(0.17,3.58) | 0.81(0.19,3.12) | ‐0.01(‐0.12,0.12) | |
| SD GOLI SC | 2.02(0.17,22.98) | 1.85(0.19,9.98) | 0.07(‐0.10,0.55) | |
| SD ETN SC + MTX | 1.78(0.98,3.28) | 1.66(0.98,2.89) | 0.05(0.00,0.13) | |
| SD ABA IV + MTX | 2.64(0.86,8.24) | 2.31(0.88,6.23) | 0.11(‐0.02,0.25) | |
| SD ABA SC + MTX | 1.95(0.52,6.80) | 1.80(0.56,5.28) | 0.07(‐0.06,0.23) | |
| SD GOLI SC + MTX | 5.93(1.54,23.52) | 4.14(1.42,11.54) | 0.26(0.06,0.53) | |
| SD ADA SC + MTX | 2.19(0.66,7.51) | 1.98(0.70,5.75) | 0.08(‐0.04,0.25) | |
| SD INF IV + MTX | 1.26(0.35,4.76) | 1.23(0.39,4.03) | 0.02(‐0.09,0.16) | |
| SD RITUX IV + MTX | 2.03(0.55,7.94) | 1.86(0.59,5.85) | 0.07(‐0.06,0.26) | |
| SD GOLI IV + MTX | 1.83(0.49,6.84) | 1.70(0.53,5.28) | 0.06(‐0.07,0.23) | |
| SD CERTO + MTX | 6.05(0.54,173.40) | 4.14(0.58,17.25) | 0.27(‐0.05,0.85) | |
| SD TOFA PO + MTX | 2.40(0.41,17.30) | 2.13(0.45,8.97) | 0.09(‐0.07,0.47) | |
| LD GOLI IV | 1.24(0.27,5.59) | 1.21(0.30,4.48) | 0.02(‐0.10,0.20) | |
| LD RITUX IV + MTX | 0.84(0.23,3.24) | 0.85(0.26,2.91) | ‐0.01(‐0.12,0.10) | |
| LD ETN SC + MTX | 1.65(0.51,5.30) | 1.56(0.55,4.24) | 0.05(‐0.06,0.21) | |
| LD GOLI IV + MTX | 0.73(0.15,3.38) | 0.75(0.18,2.98) | ‐0.02(‐0.13,0.11) | |
| HD TOCI IV | 3.97(0.79,21.11) | 3.13(0.81,10.30) | 0.18(‐0.02,0.52) | |
| HD GOLI SC | 2.63(0.51,13.94) | 2.30(0.55,8.37) | 0.11(‐0.06,0.41) | |
| HD TOCI IV + MTX | 7.26(1.70,35.12) | 4.66(1.54,13.53) | 0.31(0.07,0.62) | |
| HD GOLI SC + MTX | 5.29(1.38,21.36) | 3.84(1.31,10.96) | 0.24(0.04,0.50) | |
| HD INF IV + MTX | 1.95(0.50,7.90) | 1.80(0.54,5.80) | 0.07(‐0.06,0.27) | |
| HD TOFA PO + MTX | 6.14(1.05,42.98) | 4.19(1.05,13.49) | 0.27(0.01,0.68) | |
| SD GOLI IV | SD ADA SC | 1.16(0.12,10.30) | 1.15(0.15,8.96) | 0.01(‐0.22,0.15) |
| SD GOLI SC | 2.93(0.15,54.59) | 2.56(0.19,26.46) | 0.09(‐0.17,0.57) | |
| SD ETN SC + MTX | 2.61(0.34,18.74) | 2.38(0.42,15.27) | 0.08(‐0.16,0.22) | |
| SD ABA IV + MTX | 3.86(0.53,27.42) | 3.29(0.61,20.65) | 0.13(‐0.10,0.29) | |
| SD ABA SC + MTX | 2.85(0.34,21.22) | 2.55(0.41,16.70) | 0.09(‐0.15,0.26) | |
| SD GOLI SC + MTX | 8.70(1.00,72.73) | 5.85(1.00,37.81) | 0.28(0.00,0.56) | |
| SD ADA SC + MTX | 3.21(0.42,24.69) | 2.81(0.50,19.01) | 0.10(‐0.13,0.28) | |
| SD INF IV + MTX | 1.85(0.23,14.89) | 1.75(0.28,12.48) | 0.04(‐0.19,0.19) | |
| SD RITUX IV + MTX | 2.95(0.36,24.01) | 2.63(0.43,18.22) | 0.09(‐0.14,0.29) | |
| SD GOLI IV + MTX | 2.65(0.31,21.24) | 2.41(0.38,16.56) | 0.08(‐0.16,0.26) | |
| SD CERTO + MTX | 9.30(0.48,342.30) | 5.75(0.54,50.05) | 0.28(‐0.08,0.87) | |
| SD TOFA PO + MTX | 3.54(0.30,45.36) | 3.02(0.36,26.00) | 0.11(‐0.14,0.50) | |
| LD GOLI IV | 1.78(0.20,16.52) | 1.69(0.25,13.47) | 0.04(‐0.19,0.23) | |
| LD RITUX IV + MTX | 1.22(0.15,9.80) | 1.21(0.19,8.76) | 0.01(‐0.21,0.13) | |
| LD ETN SC + MTX | 2.42(0.28,19.81) | 2.22(0.34,15.66) | 0.07(‐0.17,0.26) | |
| LD GOLI IV + MTX | 1.07(0.11,9.71) | 1.06(0.14,8.49) | 0.00(‐0.22,0.14) | |
| HD TOCI IV | 5.76(1.72,19.49) | 4.34(1.48,14.65) | 0.19(0.05,0.42) | |
| HD GOLI SC | 3.83(0.39,38.62) | 3.22(0.45,25.05) | 0.12(‐0.12,0.43) | |
| HD TOCI IV + MTX | 10.55(2.48,49.64) | 6.46(1.81,28.75) | 0.32(0.13,0.57) | |
| HD GOLI SC + MTX | 7.76(0.92,64.05) | 5.42(0.94,35.92) | 0.26(‐0.01,0.53) | |
| HD INF IV + MTX | 2.84(0.34,23.63) | 2.53(0.41,17.70) | 0.09(‐0.15,0.29) | |
| HD TOFA PO + MTX | 9.03(0.76,112.30) | 5.86(0.81,42.45) | 0.29(‐0.04,0.70) | |
| SD GOLI SC | SD GOLI IV | 2.54(0.19,35.63) | 2.26(0.21,15.81) | 0.08(‐0.11,0.57) |
| SD ETN SC + MTX | 2.25(0.52,9.72) | 2.06(0.57,7.98) | 0.07(‐0.08,0.20) | |
| SD ABA IV + MTX | 3.33(0.79,14.04) | 2.86(0.82,10.67) | 0.12(‐0.03,0.27) | |
| SD ABA SC + MTX | 2.45(0.50,11.43) | 2.22(0.55,8.97) | 0.08(‐0.08,0.25) | |
| SD GOLI SC + MTX | 7.47(1.48,40.23) | 5.10(1.36,19.75) | 0.28(0.06,0.55) | |
| SD ADA SC + MTX | 2.77(0.62,12.74) | 2.45(0.67,9.74) | 0.10(‐0.06,0.27) | |
| SD INF IV + MTX | 1.59(0.33,7.86) | 1.53(0.38,6.60) | 0.03(‐0.11,0.18) | |
| SD RITUX IV + MTX | 2.55(0.78,8.64) | 2.29(0.80,6.92) | 0.08(‐0.03,0.24) | |
| SD GOLI IV + MTX | 2.31(0.47,11.30) | 2.10(0.52,8.80) | 0.07(‐0.08,0.25) | |
| SD CERTO + MTX | 7.77(0.58,252.40) | 5.09(0.62,27.52) | 0.28(‐0.05,0.86) | |
| SD TOFA PO + MTX | 3.07(0.41,26.15) | 2.64(0.45,14.11) | 0.11(‐0.08,0.49) | |
| LD GOLI IV | 1.55(0.43,5.55) | 1.49(0.46,4.72) | 0.03(‐0.07,0.18) | |
| LD RITUX IV + MTX | 1.06(0.22,5.21) | 1.06(0.25,4.64) | 0.00(‐0.13,0.12) | |
| LD ETN SC + MTX | 2.09(0.40,10.76) | 1.93(0.44,8.34) | 0.06(‐0.09,0.24) | |
| LD GOLI IV + MTX | 0.92(0.25,3.40) | 0.92(0.27,3.10) | 0.00(‐0.11,0.10) | |
| HD TOCI IV | 5.02(0.80,33.52) | 3.86(0.83,17.14) | 0.19(‐0.02,0.53) | |
| HD GOLI SC | 3.28(0.50,22.95) | 2.80(0.55,13.84) | 0.12(‐0.07,0.43) | |
| HD TOCI IV + MTX | 9.19(1.68,56.26) | 5.76(1.51,22.84) | 0.32(0.07,0.64) | |
| HD GOLI SC + MTX | 6.66(1.27,35.02) | 4.72(1.22,18.47) | 0.25(0.03,0.51) | |
| HD INF IV + MTX | 2.44(0.48,13.07) | 2.21(0.53,9.75) | 0.08(‐0.08,0.29) | |
| HD TOFA PO + MTX | 7.78(1.07,64.92) | 5.12(1.06,22.12) | 0.28(0.01,0.69) | |
| SD ETN SC + MTX | SD GOLI SC | 0.89(0.08,10.10) | 0.90(0.18,8.44) | ‐0.01(‐0.50,0.18) |
| SD ABA IV + MTX | 1.31(0.12,14.37) | 1.24(0.26,11.15) | 0.04(‐0.45,0.25) | |
| SD ABA SC + MTX | 0.96(0.08,11.17) | 0.96(0.18,9.10) | ‐0.01(‐0.50,0.22) | |
| SD GOLI SC + MTX | 2.96(0.34,25.94) | 2.21(0.56,16.14) | 0.18(‐0.24,0.44) | |
| SD ADA SC + MTX | 1.10(0.10,12.89) | 1.08(0.21,10.13) | 0.01(‐0.48,0.24) | |
| SD INF IV + MTX | 0.63(0.05,7.62) | 0.67(0.12,6.55) | ‐0.05(‐0.53,0.15) | |
| SD RITUX IV + MTX | 1.01(0.08,12.47) | 1.01(0.18,9.79) | 0.00(‐0.49,0.24) | |
| SD GOLI IV + MTX | 0.91(0.08,11.45) | 0.93(0.17,9.11) | ‐0.01(‐0.49,0.22) | |
| SD CERTO + MTX | 3.11(0.13,171.40) | 2.18(0.22,26.61) | 0.18(‐0.38,0.82) | |
| SD TOFA PO + MTX | 1.21(0.08,21.40) | 1.16(0.15,13.28) | 0.02(‐0.47,0.42) | |
| LD GOLI IV | 0.61(0.05,8.20) | 0.66(0.10,6.84) | ‐0.05(‐0.54,0.18) | |
| LD RITUX IV + MTX | 0.42(0.03,5.11) | 0.46(0.08,4.64) | ‐0.08(‐0.57,0.10) | |
| LD ETN SC + MTX | 0.83(0.07,10.66) | 0.85(0.15,8.61) | ‐0.02(‐0.51,0.21) | |
| LD GOLI IV + MTX | 0.37(0.03,4.99) | 0.41(0.06,4.46) | ‐0.09(‐0.57,0.10) | |
| HD TOCI IV | 1.99(0.14,28.76) | 1.69(0.26,16.67) | 0.10(‐0.41,0.48) | |
| HD GOLI SC | 1.30(0.22,8.06) | 1.23(0.37,6.71) | 0.03(‐0.32,0.24) | |
| HD TOCI IV + MTX | 3.67(0.27,50.42) | 2.51(0.48,23.04) | 0.23(‐0.29,0.59) | |
| HD GOLI SC + MTX | 2.62(0.31,23.79) | 2.05(0.52,15.43) | 0.15(‐0.27,0.42) | |
| HD INF IV + MTX | 0.98(0.08,12.35) | 0.98(0.17,9.59) | 0.00(‐0.49,0.25) | |
| HD TOFA PO + MTX | 3.07(0.20,54.35) | 2.23(0.36,21.96) | 0.18(‐0.34,0.63) | |
| SD ABA IV + MTX | SD ETN SC + MTX | 1.48(0.53,4.24) | 1.38(0.59,3.35) | 0.05(‐0.09,0.21) |
| SD ABA SC + MTX | 1.09(0.31,3.61) | 1.08(0.37,2.92) | 0.01(‐0.14,0.18) | |
| SD GOLI SC + MTX | 3.32(0.91,12.57) | 2.48(0.93,6.26) | 0.21(‐0.01,0.48) | |
| SD ADA SC + MTX | 1.23(0.40,3.93) | 1.19(0.46,3.09) | 0.03(‐0.12,0.20) | |
| SD INF IV + MTX | 0.71(0.21,2.48) | 0.74(0.25,2.17) | ‐0.04(‐0.17,0.11) | |
| SD RITUX IV + MTX | 1.13(0.32,4.15) | 1.11(0.38,3.22) | 0.02(‐0.14,0.21) | |
| SD GOLI IV + MTX | 1.02(0.29,3.55) | 1.02(0.35,2.89) | 0.00(‐0.15,0.18) | |
| SD CERTO + MTX | 3.40(0.32,96.36) | 2.50(0.37,9.56) | 0.21(‐0.12,0.80) | |
| SD TOFA PO + MTX | 1.35(0.24,9.23) | 1.28(0.28,4.96) | 0.04(‐0.15,0.42) | |
| LD GOLI IV | 0.69(0.16,2.98) | 0.73(0.19,2.49) | ‐0.04(‐0.18,0.15) | |
| LD RITUX IV + MTX | 0.47(0.14,1.68) | 0.51(0.17,1.58) | ‐0.07(‐0.20,0.05) | |
| LD ETN SC + MTX | 0.92(0.32,2.70) | 0.94(0.37,2.26) | ‐0.01(‐0.13,0.15) | |
| LD GOLI IV + MTX | 0.41(0.09,1.76) | 0.45(0.11,1.64) | ‐0.07(‐0.21,0.06) | |
| HD TOCI IV | 2.21(0.46,11.41) | 1.88(0.52,5.73) | 0.12(‐0.10,0.47) | |
| HD GOLI SC | 1.47(0.30,7.52) | 1.38(0.35,4.55) | 0.05(‐0.14,0.36) | |
| HD TOCI IV + MTX | 4.06(1.01,18.90) | 2.80(1.01,7.22) | 0.25(0.00,0.57) | |
| HD GOLI SC + MTX | 2.97(0.82,11.42) | 2.30(0.85,6.00) | 0.18(‐0.03,0.45) | |
| HD INF IV + MTX | 1.09(0.30,4.14) | 1.08(0.35,3.17) | 0.01(‐0.14,0.22) | |
| HD TOFA PO + MTX | 3.44(0.61,23.13) | 2.52(0.66,7.40) | 0.22(‐0.06,0.62) | |
| SD ABA SC + MTX | SD ABA IV + MTX | 0.74(0.29,1.75) | 0.78(0.35,1.55) | ‐0.04(‐0.17,0.09) |
| SD GOLI SC + MTX | 2.25(0.64,8.15) | 1.80(0.71,4.15) | 0.15(‐0.08,0.44) | |
| SD ADA SC + MTX | 0.83(0.33,2.17) | 0.86(0.40,1.83) | ‐0.03(‐0.16,0.13) | |
| SD INF IV + MTX | 0.48(0.15,1.60) | 0.53(0.19,1.48) | ‐0.09(‐0.24,0.07) | |
| SD RITUX IV + MTX | 0.77(0.22,2.72) | 0.81(0.29,2.19) | ‐0.04(‐0.20,0.17) | |
| SD GOLI IV + MTX | 0.69(0.21,2.32) | 0.74(0.26,1.95) | ‐0.05(‐0.21,0.14) | |
| SD CERTO + MTX | 2.30(0.22,64.08) | 1.81(0.27,6.40) | 0.16(‐0.19,0.75) | |
| SD TOFA PO + MTX | 0.91(0.17,6.04) | 0.92(0.21,3.36) | ‐0.01(‐0.21,0.37) | |
| LD GOLI IV | 0.46(0.11,1.93) | 0.52(0.15,1.70) | ‐0.09(‐0.25,0.10) | |
| LD RITUX IV + MTX | 0.32(0.10,1.08) | 0.37(0.13,1.07) | ‐0.12(‐0.27,0.01) | |
| LD ETN SC + MTX | 0.63(0.17,2.23) | 0.68(0.22,1.89) | ‐0.06(‐0.22,0.13) | |
| LD GOLI IV + MTX | 0.27(0.06,1.16) | 0.32(0.09,1.14) | ‐0.13(‐0.27,0.02) | |
| HD TOCI IV | 1.49(0.32,7.39) | 1.36(0.39,3.84) | 0.07(‐0.16,0.42) | |
| HD GOLI SC | 0.99(0.21,4.87) | 0.99(0.26,3.09) | 0.00(‐0.20,0.31) | |
| HD TOCI IV + MTX | 2.75(0.71,11.99) | 2.03(0.77,4.78) | 0.20(‐0.06,0.53) | |
| HD GOLI SC + MTX | 2.02(0.55,7.41) | 1.67(0.63,4.00) | 0.13(‐0.10,0.41) | |
| HD INF IV + MTX | 0.74(0.22,2.50) | 0.78(0.28,2.02) | ‐0.04(‐0.20,0.16) | |
| HD TOFA PO + MTX | 2.31(0.43,15.08) | 1.82(0.50,4.87) | 0.16(‐0.12,0.57) | |
| SD GOLI SC + MTX | SD ABA SC + MTX | 3.08(0.76,13.00) | 2.32(0.81,6.60) | 0.20(‐0.05,0.48) |
| SD ADA SC + MTX | 1.13(0.36,3.92) | 1.10(0.43,3.12) | 0.02(‐0.15,0.19) | |
| SD INF IV + MTX | 0.65(0.18,2.58) | 0.69(0.22,2.27) | ‐0.05(‐0.22,0.11) | |
| SD RITUX IV + MTX | 1.04(0.27,4.32) | 1.03(0.33,3.37) | 0.01(‐0.18,0.21) | |
| SD GOLI IV + MTX | 0.93(0.25,3.73) | 0.94(0.31,3.04) | ‐0.01(‐0.19,0.18) | |
| SD CERTO + MTX | 3.14(0.27,91.33) | 2.32(0.33,9.80) | 0.20(‐0.15,0.79) | |
| SD TOFA PO + MTX | 1.24(0.21,9.08) | 1.19(0.26,5.02) | 0.03(‐0.18,0.41) | |
| LD GOLI IV | 0.63(0.14,3.03) | 0.67(0.18,2.55) | ‐0.05(‐0.22,0.15) | |
| LD RITUX IV + MTX | 0.43(0.12,1.76) | 0.47(0.15,1.65) | ‐0.08(‐0.24,0.06) | |
| LD ETN SC + MTX | 0.85(0.21,3.58) | 0.87(0.26,2.88) | ‐0.02(‐0.20,0.18) | |
| LD GOLI IV + MTX | 0.37(0.08,1.84) | 0.42(0.10,1.70) | ‐0.09(‐0.25,0.06) | |
| HD TOCI IV | 2.03(0.39,11.76) | 1.74(0.46,5.96) | 0.11(‐0.13,0.46) | |
| HD GOLI SC | 1.35(0.26,7.64) | 1.28(0.31,4.78) | 0.04(‐0.17,0.36) | |
| HD TOCI IV + MTX | 3.75(0.85,19.24) | 2.60(0.89,7.76) | 0.24(‐0.03,0.57) | |
| HD GOLI SC + MTX | 2.75(0.68,11.78) | 2.15(0.74,6.29) | 0.17(‐0.07,0.45) | |
| HD INF IV + MTX | 1.00(0.26,4.19) | 1.00(0.32,3.25) | 0.00(‐0.18,0.21) | |
| HD TOFA PO + MTX | 3.16(0.54,22.86) | 2.33(0.61,7.65) | 0.20(‐0.09,0.62) | |
| SD ADA SC + MTX | SD GOLI SC + MTX | 0.37(0.09,1.49) | 0.48(0.19,1.35) | ‐0.18(‐0.46,0.07) |
| SD INF IV + MTX | 0.21(0.05,0.90) | 0.30(0.10,0.92) | ‐0.24(‐0.52,‐0.02) | |
| SD RITUX IV + MTX | 0.34(0.08,1.49) | 0.45(0.15,1.34) | ‐0.19(‐0.47,0.07) | |
| SD GOLI IV + MTX | 0.31(0.07,1.31) | 0.41(0.14,1.22) | ‐0.20(‐0.48,0.05) | |
| SD CERTO + MTX | 1.03(0.08,31.79) | 1.02(0.15,3.86) | 0.01(‐0.43,0.64) | |
| SD TOFA PO + MTX | 0.41(0.06,3.16) | 0.52(0.11,2.04) | ‐0.16(‐0.48,0.26) | |
| LD GOLI IV | 0.21(0.04,1.04) | 0.29(0.08,1.03) | ‐0.24(‐0.52,0.01) | |
| LD RITUX IV + MTX | 0.14(0.03,0.61) | 0.21(0.07,0.67) | ‐0.27(‐0.54,‐0.07) | |
| LD ETN SC + MTX | 0.28(0.06,1.23) | 0.38(0.12,1.17) | ‐0.21(‐0.49,0.04) | |
| LD GOLI IV + MTX | 0.12(0.02,0.63) | 0.18(0.05,0.70) | ‐0.28(‐0.55,‐0.06) | |
| HD TOCI IV | 0.66(0.11,3.95) | 0.76(0.21,2.34) | ‐0.08(‐0.42,0.31) | |
| HD GOLI SC | 0.44(0.13,1.52) | 0.56(0.20,1.31) | ‐0.15(‐0.37,0.09) | |
| HD TOCI IV + MTX | 1.23(0.24,6.60) | 1.13(0.41,2.97) | 0.05(‐0.31,0.42) | |
| HD GOLI SC + MTX | 0.89(0.41,1.99) | 0.93(0.55,1.57) | ‐0.02(‐0.20,0.15) | |
| HD INF IV + MTX | 0.33(0.07,1.53) | 0.43(0.14,1.36) | ‐0.19(‐0.47,0.08) | |
| HD TOFA PO + MTX | 1.04(0.16,7.84) | 1.03(0.27,3.02) | 0.01(‐0.37,0.46) | |
| SD INF IV + MTX | SD ADA SC + MTX | 0.58(0.16,2.08) | 0.62(0.20,1.86) | ‐0.06(‐0.24,0.09) |
| SD RITUX IV + MTX | 0.92(0.24,3.53) | 0.94(0.31,2.77) | ‐0.01(‐0.20,0.19) | |
| SD GOLI IV + MTX | 0.83(0.22,3.06) | 0.85(0.28,2.51) | ‐0.02(‐0.21,0.16) | |
| SD CERTO + MTX | 2.75(0.25,80.90) | 2.09(0.30,8.25) | 0.18(‐0.17,0.78) | |
| SD TOFA PO + MTX | 1.09(0.18,7.62) | 1.08(0.23,4.23) | 0.01(‐0.21,0.40) | |
| LD GOLI IV | 0.56(0.12,2.44) | 0.61(0.16,2.09) | ‐0.06(‐0.24,0.13) | |
| LD RITUX IV + MTX | 0.38(0.10,1.41) | 0.43(0.14,1.35) | ‐0.09(‐0.26,0.04) | |
| LD ETN SC + MTX | 0.76(0.19,2.89) | 0.79(0.24,2.38) | ‐0.03(‐0.22,0.15) | |
| LD GOLI IV + MTX | 0.33(0.07,1.50) | 0.38(0.09,1.42) | ‐0.10(‐0.27,0.05) | |
| HD TOCI IV | 1.80(0.35,9.44) | 1.58(0.42,4.83) | 0.09(‐0.15,0.44) | |
| HD GOLI SC | 1.19(0.23,6.33) | 1.15(0.29,3.95) | 0.02(‐0.19,0.34) | |
| HD TOCI IV + MTX | 3.30(0.75,15.65) | 2.35(0.81,6.23) | 0.23(‐0.05,0.55) | |
| HD GOLI SC + MTX | 2.40(0.61,9.56) | 1.93(0.69,5.15) | 0.15(‐0.09,0.43) | |
| HD INF IV + MTX | 0.89(0.30,2.55) | 0.91(0.36,2.11) | ‐0.02(‐0.15,0.15) | |
| HD TOFA PO + MTX | 2.79(0.48,18.97) | 2.11(0.55,6.33) | 0.19(‐0.11,0.60) | |
| SD RITUX IV + MTX | SD INF IV + MTX | 1.61(0.39,6.53) | 1.51(0.44,4.92) | 0.05(‐0.11,0.25) |
| SD GOLI IV + MTX | 1.45(0.36,5.50) | 1.38(0.41,4.35) | 0.04(‐0.12,0.22) | |
| SD CERTO + MTX | 4.83(0.41,139.90) | 3.36(0.46,14.62) | 0.25(‐0.09,0.83) | |
| SD TOFA PO + MTX | 1.90(0.30,14.52) | 1.73(0.34,7.58) | 0.07(‐0.12,0.46) | |
| LD GOLI IV | 0.98(0.19,4.59) | 0.98(0.23,3.74) | 0.00(‐0.15,0.18) | |
| LD RITUX IV + MTX | 0.67(0.26,1.69) | 0.69(0.30,1.60) | ‐0.03(‐0.13,0.05) | |
| LD ETN SC + MTX | 1.31(0.30,5.36) | 1.27(0.35,4.26) | 0.03(‐0.13,0.21) | |
| LD GOLI IV + MTX | 0.58(0.11,2.82) | 0.60(0.13,2.53) | ‐0.04(‐0.18,0.10) | |
| HD TOCI IV | 3.11(0.58,17.79) | 2.52(0.63,8.80) | 0.16(‐0.07,0.50) | |
| HD GOLI SC | 2.07(0.38,11.71) | 1.84(0.43,7.08) | 0.09(‐0.10,0.40) | |
| HD TOCI IV + MTX | 5.76(1.23,29.64) | 3.78(1.18,11.45) | 0.29(0.03,0.61) | |
| HD GOLI SC + MTX | 4.20(0.99,17.74) | 3.10(0.99,9.28) | 0.22(0.00,0.48) | |
| HD INF IV + MTX | 1.55(0.37,6.58) | 1.46(0.42,4.93) | 0.05(‐0.11,0.25) | |
| HD TOFA PO + MTX | 4.86(0.78,36.18) | 3.38(0.81,11.54) | 0.25(‐0.03,0.66) | |
| SD GOLI IV + MTX | SD RITUX IV + MTX | 0.90(0.21,3.64) | 0.91(0.28,2.98) | ‐0.01(‐0.22,0.18) |
| SD CERTO + MTX | 3.00(0.26,85.82) | 2.23(0.32,9.56) | 0.19(‐0.17,0.79) | |
| SD TOFA PO + MTX | 1.19(0.17,9.07) | 1.15(0.22,5.06) | 0.02(‐0.21,0.41) | |
| LD GOLI IV | 0.61(0.19,1.95) | 0.65(0.23,1.76) | ‐0.05(‐0.21,0.09) | |
| LD RITUX IV + MTX | 0.42(0.10,1.77) | 0.46(0.13,1.66) | ‐0.08(‐0.28,0.06) | |
| LD ETN SC + MTX | 0.82(0.19,3.57) | 0.84(0.24,2.91) | ‐0.02(‐0.23,0.17) | |
| LD GOLI IV + MTX | 0.36(0.10,1.22) | 0.40(0.13,1.18) | ‐0.09(‐0.25,0.02) | |
| HD TOCI IV | 1.96(0.35,10.94) | 1.68(0.43,5.67) | 0.10(‐0.16,0.45) | |
| HD GOLI SC | 1.28(0.22,7.76) | 1.23(0.29,4.76) | 0.03(‐0.20,0.36) | |
| HD TOCI IV + MTX | 3.60(0.76,18.40) | 2.51(0.81,7.46) | 0.24(‐0.05,0.56) | |
| HD GOLI SC + MTX | 2.61(0.59,11.59) | 2.06(0.67,6.26) | 0.17(‐0.09,0.44) | |
| HD INF IV + MTX | 0.96(0.22,4.22) | 0.97(0.28,3.26) | 0.00(‐0.21,0.21) | |
| HD TOFA PO + MTX | 3.03(0.46,22.18) | 2.25(0.54,7.62) | 0.20(‐0.12,0.61) | |
| SD CERTO + MTX | SD GOLI IV + MTX | 3.38(0.30,95.03) | 2.47(0.35,10.37) | 0.21(‐0.15,0.80) |
| SD TOFA PO + MTX | 1.33(0.21,10.15) | 1.26(0.26,5.55) | 0.04(‐0.19,0.42) | |
| LD GOLI IV | 0.68(0.14,3.34) | 0.71(0.17,2.77) | ‐0.04(‐0.22,0.15) | |
| LD RITUX IV + MTX | 0.46(0.12,1.94) | 0.50(0.15,1.80) | ‐0.07(‐0.24,0.06) | |
| LD ETN SC + MTX | 0.91(0.21,3.88) | 0.92(0.26,3.14) | ‐0.01(‐0.20,0.18) | |
| LD GOLI IV + MTX | 0.40(0.08,2.00) | 0.44(0.10,1.85) | ‐0.08(‐0.25,0.07) | |
| HD TOCI IV | 2.18(0.40,12.48) | 1.84(0.48,6.34) | 0.12(‐0.13,0.47) | |
| HD GOLI SC | 1.43(0.25,8.39) | 1.34(0.32,5.14) | 0.05(‐0.17,0.36) | |
| HD TOCI IV + MTX | 3.99(0.88,20.79) | 2.74(0.91,8.32) | 0.25(‐0.02,0.58) | |
| HD GOLI SC + MTX | 2.92(0.68,12.70) | 2.27(0.74,6.77) | 0.18(‐0.06,0.45) | |
| HD INF IV + MTX | 1.07(0.25,4.68) | 1.06(0.31,3.59) | 0.01(‐0.18,0.22) | |
| HD TOFA PO + MTX | 3.37(0.53,25.33) | 2.47(0.60,8.31) | 0.21(‐0.09,0.63) | |
| SD TOFA PO + MTX | SD CERTO + MTX | 0.39(0.01,6.54) | 0.53(0.08,4.31) | ‐0.16(‐0.78,0.32) |
| LD GOLI IV | 0.20(0.01,2.58) | 0.29(0.06,2.25) | ‐0.25(‐0.83,0.10) | |
| LD RITUX IV + MTX | 0.14(0.00,1.63) | 0.21(0.04,1.55) | ‐0.28(‐0.86,0.04) | |
| LD ETN SC + MTX | 0.27(0.01,3.26) | 0.38(0.08,2.75) | ‐0.22(‐0.81,0.14) | |
| LD GOLI IV + MTX | 0.12(0.00,1.60) | 0.18(0.03,1.53) | ‐0.29(‐0.87,0.04) | |
| HD TOCI IV | 0.63(0.02,9.38) | 0.74(0.15,5.59) | ‐0.09(‐0.72,0.39) | |
| HD GOLI SC | 0.43(0.01,6.41) | 0.56(0.10,4.40) | ‐0.15(‐0.78,0.29) | |
| HD TOCI IV + MTX | 1.18(0.04,15.85) | 1.10(0.28,7.55) | 0.04(‐0.60,0.51) | |
| HD GOLI SC + MTX | 0.86(0.03,10.85) | 0.91(0.23,6.33) | ‐0.03(‐0.66,0.40) | |
| HD INF IV + MTX | 0.32(0.01,3.83) | 0.44(0.09,3.13) | ‐0.20(‐0.80,0.17) | |
| HD TOFA PO + MTX | 1.00(0.03,16.78) | 1.00(0.20,7.22) | 0.00(‐0.66,0.53) | |
| LD GOLI IV | SD TOFA PO + MTX | 0.51(0.06,3.84) | 0.57(0.11,3.26) | ‐0.07(‐0.46,0.15) |
| LD RITUX IV + MTX | 0.35(0.05,2.23) | 0.40(0.09,2.08) | ‐0.11(‐0.49,0.06) | |
| LD ETN SC + MTX | 0.69(0.09,4.57) | 0.73(0.16,3.73) | ‐0.05(‐0.43,0.18) | |
| LD GOLI IV + MTX | 0.30(0.03,2.31) | 0.35(0.06,2.12) | ‐0.11(‐0.49,0.07) | |
| HD TOCI IV | 1.63(0.17,14.23) | 1.45(0.29,7.68) | 0.08(‐0.34,0.46) | |
| HD GOLI SC | 1.08(0.12,9.33) | 1.06(0.20,6.10) | 0.01(‐0.38,0.35) | |
| HD TOCI IV + MTX | 3.03(0.35,24.24) | 2.17(0.52,10.32) | 0.21(‐0.23,0.57) | |
| HD GOLI SC + MTX | 2.18(0.29,14.76) | 1.78(0.45,8.32) | 0.14(‐0.27,0.45) | |
| HD INF IV + MTX | 0.81(0.10,5.60) | 0.84(0.19,4.34) | ‐0.03(‐0.41,0.22) | |
| HD TOFA PO + MTX | 2.54(0.77,8.35) | 1.90(0.84,4.96) | 0.16(‐0.05,0.42) | |
| LD RITUX IV + MTX | LD GOLI IV | 0.68(0.14,3.49) | 0.70(0.18,3.15) | ‐0.03(‐0.21,0.10) |
| LD ETN SC + MTX | 1.34(0.26,6.97) | 1.29(0.32,5.50) | 0.03(‐0.16,0.22) | |
| LD GOLI IV + MTX | 0.59(0.16,2.13) | 0.62(0.19,1.99) | ‐0.04(‐0.18,0.06) | |
| HD TOCI IV | 3.21(0.52,21.14) | 2.57(0.58,10.98) | 0.16(‐0.09,0.50) | |
| HD GOLI SC | 2.11(0.33,14.71) | 1.88(0.39,8.95) | 0.09(‐0.13,0.40) | |
| HD TOCI IV + MTX | 5.89(1.07,35.70) | 3.84(1.05,14.58) | 0.29(0.01,0.61) | |
| HD GOLI SC + MTX | 4.28(0.85,22.51) | 3.16(0.88,12.10) | 0.22(‐0.03,0.49) | |
| HD INF IV + MTX | 1.57(0.32,8.29) | 1.48(0.38,6.27) | 0.05(‐0.15,0.26) | |
| HD TOFA PO + MTX | 5.02(0.68,41.56) | 3.45(0.73,14.51) | 0.25(‐0.05,0.66) | |
| LD ETN SC + MTX | LD RITUX IV + MTX | 1.97(0.45,8.35) | 1.83(0.49,6.47) | 0.06(‐0.07,0.24) |
| LD GOLI IV + MTX | 0.87(0.17,4.33) | 0.87(0.19,3.78) | ‐0.01(‐0.12,0.12) | |
| HD TOCI IV | 4.73(0.84,27.17) | 3.68(0.86,13.18) | 0.19(‐0.02,0.53) | |
| HD GOLI SC | 3.09(0.56,17.99) | 2.66(0.59,10.63) | 0.12(‐0.05,0.42) | |
| HD TOCI IV + MTX | 8.66(1.83,45.28) | 5.47(1.63,17.09) | 0.32(0.08,0.64) | |
| HD GOLI SC + MTX | 6.35(1.46,27.01) | 4.52(1.36,13.87) | 0.25(0.05,0.51) | |
| HD INF IV + MTX | 2.32(0.54,9.92) | 2.11(0.57,7.28) | 0.08(‐0.06,0.28) | |
| HD TOFA PO + MTX | 7.28(1.16,54.51) | 4.88(1.13,17.36) | 0.28(0.02,0.69) | |
| LD GOLI IV + MTX | LD ETN SC + MTX | 0.44(0.08,2.25) | 0.48(0.11,2.06) | ‐0.07(‐0.25,0.08) |
| HD TOCI IV | 2.39(0.42,14.52) | 2.00(0.49,7.43) | 0.13(‐0.12,0.48) | |
| HD GOLI SC | 1.58(0.27,9.48) | 1.46(0.33,5.95) | 0.06(‐0.17,0.37) | |
| HD TOCI IV + MTX | 4.41(0.89,24.33) | 2.98(0.92,9.81) | 0.26(‐0.02,0.59) | |
| HD GOLI SC + MTX | 3.20(0.73,14.55) | 2.45(0.79,7.88) | 0.19(‐0.05,0.46) | |
| HD INF IV + MTX | 1.17(0.26,5.51) | 1.15(0.32,4.19) | 0.02(‐0.18,0.23) | |
| HD TOFA PO + MTX | 3.68(0.58,28.24) | 2.65(0.64,9.74) | 0.22(‐0.08,0.63) | |
| HD TOCI IV | LD GOLI IV + MTX | 5.42(0.85,36.93) | 4.15(0.87,18.80) | 0.20(‐0.02,0.54) |
| HD GOLI SC | 3.57(0.54,25.19) | 3.03(0.59,15.30) | 0.13(‐0.06,0.43) | |
| HD TOCI IV + MTX | 9.93(1.80,60.87) | 6.18(1.59,25.14) | 0.33(0.08,0.64) | |
| HD GOLI SC + MTX | 7.23(1.42,39.03) | 5.08(1.33,20.87) | 0.26(0.05,0.52) | |
| HD INF IV + MTX | 2.67(0.52,14.26) | 2.40(0.56,10.66) | 0.09(‐0.07,0.29) | |
| HD TOFA PO + MTX | 8.50(1.13,72.78) | 5.57(1.11,24.42) | 0.29(0.01,0.70) | |
| HD GOLI SC | HD TOCI IV | 0.66(0.09,4.91) | 0.73(0.17,3.28) | ‐0.07(‐0.44,0.29) |
| HD TOCI IV + MTX | 1.83(0.81,4.61) | 1.46(0.88,3.04) | 0.12(‐0.05,0.31) | |
| HD GOLI SC + MTX | 1.35(0.23,7.71) | 1.23(0.39,4.44) | 0.06(‐0.33,0.39) | |
| HD INF IV + MTX | 0.49(0.08,2.84) | 0.58(0.16,2.31) | ‐0.11(‐0.46,0.16) | |
| HD TOFA PO + MTX | 1.55(0.18,14.57) | 1.33(0.31,5.42) | 0.09(‐0.35,0.55) | |
| HD TOCI IV + MTX | HD GOLI SC | 2.78(0.43,18.85) | 2.03(0.57,8.00) | 0.20(‐0.18,0.55) |
| HD GOLI SC + MTX | 2.00(0.60,7.01) | 1.65(0.71,4.74) | 0.12(‐0.11,0.34) | |
| HD INF IV + MTX | 0.74(0.12,4.36) | 0.79(0.20,3.43) | ‐0.04(‐0.36,0.20) | |
| HD TOFA PO + MTX | 2.37(0.29,21.00) | 1.83(0.41,7.89) | 0.16(‐0.23,0.59) | |
| HD GOLI SC + MTX | HD TOCI IV + MTX | 0.73(0.13,3.62) | 0.82(0.30,2.30) | ‐0.07(‐0.44,0.28) |
| HD INF IV + MTX | 0.27(0.05,1.32) | 0.39(0.12,1.22) | ‐0.24(‐0.57,0.05) | |
| HD TOFA PO + MTX | 0.84(0.10,7.14) | 0.90(0.23,2.86) | ‐0.04(‐0.47,0.44) | |
| HD INF IV + MTX | HD GOLI SC + MTX | 0.37(0.08,1.66) | 0.47(0.15,1.46) | ‐0.17(‐0.45,0.09) |
| HD TOFA PO + MTX | 1.16(0.18,8.74) | 1.10(0.29,3.31) | 0.03(‐0.34,0.48) | |
| HD TOFA PO + MTX | HD INF IV + MTX | 3.12(0.48,24.05) | 2.31(0.56,8.31) | 0.20(‐0.11,0.62) |
| Random‐effects model | Residual deviance | 75.74 vs 74 data points | ||
| Deviance information criteria | 478.266 | |||
| Fixed‐effect model | Residual deviance | 113.5 vs 74 data points | ||
| Deviance information criteria | 504.534 | |||
| Note | ||||
| Total participants | 13,479 | |||
| Total studies | 29 | |||
| 2‐arm | 16 | |||
| 3‐arm | 11 | |||
| 4‐arm | 1 | |||
| 5‐arm | 1 | |||
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