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. 2014 May 27;2014(5):CD009108. doi: 10.1002/14651858.CD009108.pub2
Summary of results J: Relief of photophobia within two hours in placebo‐controlled studies
Route of administration Dose
 (mg) Number of Number with outcome/total Percent with outcome Relative benefit
 (95% CI) NNT (95% CI)
Studies Participants Active Placebo Active Placebo
In participants with moderate or severe baseline pain
Oral 25 3 411 97/240 35/171 40 20 1.8 (1.3 to 2.5) 5.0 (3.5 to 8.9)
Oral 50 6 1144 284/638 160/506 45 32 1.4 (1.2 to 1.7) 7.8 (5.4 to 14)
Oral 100 9 2494 834/1703 201/791 49 25 1.9 (1.6 to 2.1) 4.2 (3.7 to 5.1)
Subcutaneous 6 3 631 245/343 105/288 71 36 1.9 (1.6 to 2.2) 2.9 (2.4 to 3.6)
Intranasal 20 3 1021 314/643 89/378 49 24 2.1 (1.7 to 2.5) 4.0 (3.2 to 5.1)
In participants with mild baseline pain
Oral 50 3 483 125/237 44/246 53 18 3.0 (2.2 to 4.0) 2.9 (2.3 to 3.7)
Oral 100 3 475 131/229 44/246 57 18 3.2 (2.4 to 4.3) 2.5 (2.1 to 3.2)