. 2019 Feb 28;266(5):1203–1210. doi: 10.1007/s00415-019-09250-y

Table 2.

Backward elimination regression analysis for cognitive decline as defined by the MoCA and neuropsychological tests

	HR	95.0% CI for HR		p value	Wald
	HR	Lower	Upper	p value	Wald
MoCA-defined CI
CSF Aβ1–42 levels pg/mL	0.998	0.996	1.000	0.092	2.840
CSF total tau pg/mL	1.009	0.995	1.023	0.217	1.522
Caudate [¹²³I]FP-CIT	0.945	0.538	1.660	0.843	0.039
Age at screening	1.048	1.024	1.073	< 0.001	15.377
Gender	1.318	0.791	2.195	0.289	1.123
Neuropsychological test-defined CI
CSF Aβ1–42 levels pg/mL	0.996	0.992	0.999	0.025	5.035
CSF total tau pg/mL	1.023	1.002	1.044	0.031	4.680
Caudate [¹²³I]FP-CIT	0.332	0.115	0.960	0.042	4.146
Age at screening	1.076	1.028	1.126	0.001	10.084
Gender	1.479	0.626	3.490	0.372	0.797