Table 3:
Cognitive Aging (Slope) Associations
| Full Sample (n=19,594) | Genetic Sample (n=10,784) | |||||
|---|---|---|---|---|---|---|
| Coef. | SE | P | Coef. | Robust SE | P | |
| Female | 0.02 | 0.012 | 0.072 | 0.00 | 0.013 | 0.966 | 
| Race/Ethnicity | ||||||
| (Reference=Non-Hispanic White) | ||||||
| Non-Hispanic Black | 0.01 | 0.020 | 0.758 | 0.01 | 0.024 | 0.558 | 
| Hispanic | −0.08 | 0.024 | 0.001 | −0.04 | 0.026 | 0.139 | 
| Other | −0.05 | 0.045 | 0.247 | 0.07 | 0.051 | 0.160 | 
| Education | ||||||
| (Reference=College) | ||||||
| <HS | 0.04 | 0.019 | 0.023 | 0.04 | 0.022 | 0.042 | 
| HS/GED | 0.03 | 0.016 | 0.089 | 0.03 | 0.017 | 0.054 | 
| Some College | 0.03 | 0.017 | 0.070 | 0.01 | 0.018 | 0.780 | 
| Mean Age Across Waves | 0.02 | 0.001 | <0.001 | 0.01 | 0.004 | <0.001 | 
| Baseline Heart Disease | 0.00 | 0.017 | 0.854 | −0.01 | 0.020 | 0.461 | 
| Baseline Diabetes | 0.06 | 0.020 | 0.002 | 0.06 | 0.022 | 0.010 | 
| Baseline BMI | ||||||
| (Reference=Normal) | ||||||
| Underweight | 0.02 | 0.057 | 0.683 | 0.11 | 0.075 | 0.154 | 
| Overweight | −0.02 | 0.014 | 0.140 | 0.00 | 0.015 | 0.992 | 
| Obese | −0.05 | 0.016 | 0.001 | −0.03 | 0.017 | 0.095 | 
| APOE ε4 | ||||||
| (Reference=0) | ||||||
| 1 | -- | -- | -- | 0.08 | 0.014 | <0.001 | 
| 2 | -- | -- | -- | 0.18 | 0.045 | <0.001 | 
| PRS | -- | -- | -- | 0.01 | 0.006 | 0.036 |