TABLE 15.
Calibration of Risk Model for Progression to Advanced Age-Related Macular Degeneration. a
Risk (decile) |
n | Observed # events |
Expected # events |
---|---|---|---|
1 | 113 | 14.83 | 7.72 |
2 | 115 | 11.61 | 12.58 |
3 | 114 | 17.09 | 16.23 |
4 | 115 | 27.12 | 18.95 |
5 | 115 | 14.5 | 22.04 |
6 | 114 | 30.49 | 25.24 |
7 | 114 | 20.12 | 29.52 |
8 | 116 | 40.55 | 35.03 |
9 | 114 | 44.67 | 40.54 |
10 | 114 | 45.98 | 55.36 |
total | 1144 | 266.98 | 263.21 |
Ratio (expected/observed) = 0.986 (95% CI 0.87, 1.11); Chi-square = 0.054; P value= 0.816 (indicating adequate calibration of the model).
Data was based on progression over 5 years comparing observed and expected number of eyes progressing in the validation dataset according to deciles of the risk score from the derivation sample among eyes with baseline intermediate AMD.