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. 2019 Feb 28;19(2):191–199. doi: 10.1007/s10238-019-00548-9

Table 2.

Serum concentrations of proteins tested in relation to clinicopathological parameters of oesophageal cancer (OC)

Group tested CXCL-8 (pg/ml) CRP (mg/l) CEA (ng/ml) SCC-Ag (ng/ml)
TNM stage (1 + 2)
 Median 16.65 8.50 1.50 2.20
 Range 8.55–120.66 0.50–109.10 0.20–65.06 0.50–6.70
TNM (3)
 Median 19.72 5.00 1.51 2.00
 Range 6.34–191.80 0.20–85.80 0.20–25.80 0.50–3.10
TNM (4)
 Median 28.60 23.60 1.60 2.90
 Range 11.10–82.82 2.70–277.00 0.10–6.30 0.70–9.10
pb Kruskal–Wallis test 0.16 0.12 0.76 0.01
Pc post hoc Dwass–Steel–Critchlow–Fligner Kruskal–Wallis test
 1 + 2 versus 3 0.85 0.98 0.92 0.504
 1 + 2 versus 4 0.24 0.32 0.99 0.32
 3 versus 4 0.27 0.12 0.73 0.004
T factor (T1 + 2)
 Median 16.28 6.25 1.49 2.50
 Range 8.55–40.72 0.50–109.10 0.20–10.10 0.50–6.70
T factor (T3)
 Median 22.76 6.00 1.40 2.10
 Range 6.34–191.80 0.20–85.80 0.20–65.06 0.50–5.00
T factor (T4)
 Median 28.60 35.90 2.10 2.90
 Range 19.58–82.82 5.20–277.00 0.10–5.00 0.70–9.10
pb Kruskal–Wallis test 0.041 0.021 0.77 0.009
pc post hoc Dwass–Steel–Critchlow–Fligner Kruskal–Wallis test
 1 + 2 versus 3 0.367 0.939 0.901 0.196
 1 + 2 versus 4 0.030 0.037 0.696 0.630
 3 versus 4 0.224 0.033 0.930 0.010
N factor (N0)
 Median 16.65 8.50 1.47 2.20
 Range 8.55–120.66 0.50–126.30 0.20–65.06 0.50–9.10
N factor (N1)
 Median 25.07 11.00 1.62 2.50
 Range 6.34–191.80 0.20–277.00 0.10–25.80 0.50–5.80
pa Manna–Whitney test 0.36 0.60 0.86 0.90
M factor (M0)
 Median 20.35 8.30 1.66 2.20
 Range 6.34–191.80 0.20–126.30 0.10–65.06 0.50–9.10
M factor (M1)
 Median 28.14 13.05 1.28 2.55
 Range 11.10–62.46 2.70–277.00 0.63–6.30 0.70–5.00
pa Manna–Whitney test 0.34 0.34 0.95 0.42

aStatistically significant when p < 0.05 in Mann–Whitney test

bStatistically significant when p < 0.05 in Kruskal–Wallis test

cStatistically significant when p < 0.05 in post hoc Dwass–Steel–Critchlow–Fligner Kruskal–Wallis test