Preference weight of 1 (very important) was assigned to each outcome at a time with the rest of outcomes set to 0 (not important)
| rank | No preference |
Adverse event |
Hypoglyce mia |
Stroke | MI | HbA1c | Body weight |
Injection | Daily glucose testing |
Cost | Nephro pathy |
Retino pathy |
Neuro pathy |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1st | SGLT-2-i 1.00 [0.78,1.37] |
SGLT-2-i* 1.00 [0.81,1.17] |
GLP-1* 1.00 [0.97,1.02] |
GLP-1 1.00 [0.90,1.10] |
SGLT-2-i 1.00 [0.90,1.26] |
GLP-1 1.00 [0.78,1.37] |
GLP-1 1.00 [0.73,1.27] |
SGLT-2-i 1.00 [1.00,1.00] |
GLP-1* 1.00 [1.00,1.00] |
SU 1.00 [0.99,1.01] |
GLP-1 1.00 [0.53,1.45] |
GLP-1 1.00 [0.53,1.45] |
GLP-1 1.00 [0.53,1.45] |
| 2nd | TZD 0.99 [0.83, 1.28] |
TZD* 1.00 [0.73, 1.27] |
SGLT-2-i* 1.00 [0.98, 1.02] |
Basal insulin* 0.89 [0.00, 1.72] |
GLP-1* 0.64 [0.00, 1.30] |
Basal insulin 0.70 [0.05, 1.35] |
SGLT-2-i 0.76 [0.58,0.94] |
TZD 1.00 [1.00,1.00] |
SGLT-2-i* 1.00 [0.91, 1.08] |
TZD 0.80 [0.61, 0.99] |
Basal insulin 0.71 [0.05, 1.33] |
Basal insulin 0.71 [0.05, 1.33] |
Basal insulin 0.71 [0.05, 1.33] |
| 3rd | SU 0.98 [0.85,1.27] |
SU* 1.00 [0.65,1.27] |
DPP-4* 1.00 [0.98, 1.02] |
SGLT-2-i* 0.89 [0.73, 1.05] |
Basal insulin* 0.64 [0.18, 1.11] |
TZD 0.65 [0.37,0.93] |
DPP-4* 0.58 [0.35, 0.82] |
SU 1.00 [1.00,1.00] |
DPP-4* 1.00 [0.91, 1.08] |
Basal insulin 0.61 [0.48,0.74] |
TZD 0.66 [0.38,0.93] |
TZD 0.66 [0.38,0.93] |
TZD 0.66 [0.38,0.93] |
| 4th | GLP-1 0.96 [0.71, 1.29] |
GLP-1* 1.00 [0.62, 1.31] |
TZD* 1.00 [0.98, 1.02] |
DPP-4* 0.89 [0.13, 1.65] |
DPP-4* 0.64 [0.42, 0.86] |
SGLT2-i* 0.61 [0.03, 1.19] |
TZD* 0.58 [0.36, 0.82] |
DPP-4 1.00 [1.00,1.00] |
SU* 1.00 [0.91, 1.08] |
DPP-4 0.52 [0.51, 0.54] |
SGLT2-i* 0.62 [0.04, 1.18] |
SGLT2-i* 0.62 [0.04, 1.18] |
SGLT2-i* 0.62 [0.04, 1.18] |
| 5th | DPP-4 0.85 [0.71, 1.20] |
DPP-4* 1.00 [0.60,1.40] |
SU 0.77 [0.73,0.80] |
TZD* 0.89 [0.53,1.25] |
TZD* 0.64 [0.27,1.02] |
SU* 0.61 [0.32, 0.91] |
SU 0.58 [0.42,0.74] |
GLP-1 0.00 [0.00,0.00] |
TZD 0.91 [0.82,0.99] |
SGLT2-i 0.47 [0.46, 0.47] |
SU* 0.62 [0.32, 0.92] |
SU* 0.62 [0.32, 0.92] |
SU* 0.62 [0.32, 0.92] |
| 6th | Basal insulin 0.65 [0.23, 1.20] |
Basal insulin* 1.00 [0.00, 2.00] |
Basal insulin 0.04 [0.00, 0.08] |
SU* 0.89 [0.55, 1.23] |
SU* 0.64 [0.16, 1.13] |
DPP-4 0.35 [0.00,0.70] |
Basal insulin 0.58 [0.00, 1.17] |
Basal insulin 0.00 [0.00,0.00] |
Basal insulin 0.32 [0.00, 0.64] |
GLP-1 0.18 [0.00, 0.35] |
DPP-4 0.36 [0.00,0.71] |
DPP-4 0.36 [0.00,0.71] |
DPP-4 0.36 [0.00,0.71] |