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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: J Dev Orig Health Dis. 2018 Oct 26;10(2):164–175. doi: 10.1017/S2040174418000764

Table 2. Quantification of CD3 and F4/80 staining in pancreatic sections of F3 adult male offspring.

Data are normalized to total analysis area and presented as mean (SEM). P values are from Dunnett’s-test performed on log-transformed data, where required (F4/80 islets, F4/80 lymph nodes, F4/80 excluding islets and lymph nodes). One animal per litter; N= 6 litters per group.

Control
(mm2/mm2)		 LowerB (mm2/mm2) UpperB (mm2/mm2) LowerB vs
Control
(p value)		 UpperB vs
Control
(p value)
Area of Percent Positive CD3 staining in islets/Total Analysis Area 15.90 (5.81) 23.51 (5.81) 45.27 (5.81) 0.56 0.01
Area of Percent Positive CD3 staining in pancreas excluding islets and lymph nodes/Total Analysis Area 21.19 (4.13) 24.88 (4.13) 49.67 (4.13) 0.75 0.01
Area of Percent Positive CD3 staining in pancreatic lymph nodes/Total Analysis Area 21.89
(10.16)		 24.83
(10.16)		 46.31
(10.16)		 0.97 0.19
Area of Percent Positive F4/80 staining in islets/Total Analysis Area 0.20 (0.48) 2.19 (0.48) 1.53 (0.48) 0.03 0.47
Area of Percent Positive F4/80 staining in pancreas excluding islets and lymph nodes/Total Analysis Area 0.58 (0.91) 4.50 (0.91) 3.79 (0.91) 0.01 0.02
Area of Percent Positive F4/80 staining in pancreatic lymph nodes/Total Analysis Area 0.70 (2.06) 8.44 (2.06) 4.81 (2.06) 0.18 0.59