Table 3. Univariable Cox regression analysis for the prediction of the composite endpoints.
| Variables | Hazard ratio | 95% confidence interval | p-value |
|---|---|---|---|
| Age, per 10 years | 1.30 | 0.98–1.74 | 0.073 |
| Female sex | 1.17 | 0.56–2.45 | 0.679 |
| AF | 1.64 | 0.89–3.04 | 0.112 |
| Hypertension | 1.36 | 0.73–2.52 | 0.332 |
| Diabetes | 1.54 | 0.75–3.14 | 0.237 |
| Prior stroke | 3.84 | 1.87–7.92 | < 0.001 |
| CHA2DS2-VASc score ≥ 2 | 1.76 | 0.86–3.59 | 0.121 |
| Anticoagulation | 1.02 | 0.54–1.94 | 0.948 |
| Renin-angiotensin system blocker | 1.87 | 0.57–6.17 | 0.301 |
| Symptomatic | 1.57 | 0.81–3.04 | 0.182 |
| LVEF ≤ 65% | 1.07 | 0.58–1.98 | 0.828 |
| LVMI > 115 g/m2 | 1.86 | 0.97–3.56 | 0.063 |
| LAVI > 50 mL/m2 | 4.19 | 2.05–8.57 | < 0.001 |
| MVA by planimetry ≤ 1.75 cm2 | 1.03 | 0.56–1.91 | 0.916 |
| MDPG > 3.5 mmHg | 1.13 | 0.61–2.09 | 0.699 |
| SPAP > 30 mmHg | 1.12 | 0.60–2.07 | 0.723 |
| Cn ≤ 7.2 mL/mmHg | 1.24 | 0.67–2.29 | 0.495 |
AF: atrial fibrillation, Cn: net atrioventricular compliance, LAVI: left atrial volume index, LVEF: left ventricular ejection fraction, LVMI: left ventricular mass index, MDPG: mean diastolic pressure gradient, MVA: mitral valve area, SPAP: systolic pulmonary artery pressure.