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. 2019 Apr 11;20(5):791–800. doi: 10.3348/kjr.2018.0474

Table 3. Association between Diffusion Parameters and Pathologic Diagnoses.

Parameter (x 10-3 mm2/sec) ADC Ds Df f* DDC α* MD MK*
Benign (n = 18) 0.0010 (0.0004) 0.0010 (0.0004) 0.0138 (0.0414) 0.2300 (0.1400) 0.0016 (0.0023) 0.4450 (0.1600) 0.0022 (0.0013) 0.9750 (0.2900)
Malignant (n = 63) 0.0015 (0.0006) 0.0015 (0.0006) 0.0087 (0.0135) 0.2300 (0.1900) 0.0023 (0.0014) 0.6800 (0.1300) 0.0027 (0.0012) 0.6660 (0.3000)
p 0.003 0.001 0.388 0.959 0.578 < 0.001 0.420 < 0.001
ccRCC (n = 46) 0.0016 (0.0004) 0.0016 (0.0004) 0.0095 (0.0172) 0.3250 (0.1800) 0.0024 (0.0005) 0.6550 (0.1400) 0.0028 (0.0006) 0.6200 (0.1800)
Non-ccRCC (n = 17) 0.0010 (0.0004) 0.0010 (0.0005) 0.0078 (0.0124) 0.1500 (0.1300) 0.0012 (0.0005) 0.7000 (0.0700) 0.0016 (0.0007) 0.9000 (0.1600)
p < 0.001 < 0.001 0.143 < 0.001 < 0.001 0.112 < 0.001 < 0.001
Low-grade (n = 39) 0.0017 (0.0003) 0.0017 (0.0003) 0.0087 (0.0170) 0.3300 (0.1700) 0.0025 (0.0006) 0.6700 (0.1400) 0.0028 (0.0006) 0.6000 (0.1900)
High-grade (n = 7) 0.0014 (0.0005) 0.0011 (0.0007) 0.0116 (0.0224) 0.2200 (0.1900) 0.0021 (0.0014) 0.6000 (0.1300) 0.0028 (0.0010) 0.7500 (0.1600)
p 0.018 0.010 0.291 0.183 0.087 0.076 0.291 0.002

Data are medians with interquartile range in parentheses. *f, α, and MK have no units, p value from statistical comparison between benign and malignant lesions, between ccRCC and non-ccRCC, between low-grade and high-grade ccRCC, respectively, by using Mann-Whitney U test. ADC = apparent diffusion coefficient, ccRCC = clear cell renal cell carcinoma, DDC = distributed diffusion coefficient, Df = fast diffusion coefficient, Ds = slow diffusion coefficient, f = fraction of fast diffusion, MD = mean diffusivity, MK = mean kurtosis, α = anomalous exponent term