Table 2. Total number of tNR2B and pNR2B positive neurons on ipsilateral and contralateral sides for all groups 3 days after formalin injection (n=8).
| Group | Control | DM | (I 0.5) | (I 1.0) |
|---|---|---|---|---|
| tNR2B | ||||
| Ipsilateral | 1,151±152.5 | 1,849±144a | 846±243b,c | 402±116d,e |
| Contralateral | 1,032±190.1 | 1,622±274.1a | 708±180.5b,c | 339±93.2d,f |
| pNR2B | ||||
| Ipsilateral | 1,401±177.9 | 1,676±236.4b | 560±112.4d | 436±87.5d |
| Contralateral | 1,255±236.4 | 1,375±251.4b | 464±115.9d | 399±90.9d |
Values are presented as mean±standard deviation.
tNR2B, total NR2B subunit; pNR2B, phosphorylated NR2B subunit; DM, diabetes mellitus.
aP<0.001 compared to control group, bP<0.05 compared to control group, cP<0.001 compared to DM group, dP<0.001 compared to DM and control groups, eP<0.001 compared to (I 0.5) group, fP<0.05 compared to (I 0.5) group.