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. 2019 Feb 14;28(5):1191–1199. doi: 10.1007/s11136-019-02117-9

Table 4.

Disutility estimates from the GEE model of AE health states from reference Base State 2 [estimated mean utility = 0.64 (SD 0.27)]

Adverse event Estimate Standard error estimates p value Lower 95% CI Upper 95% CI
Intercept 0.37 0.02 < 0.0001 0.32 0.41
Alopecia − 0.04 0.01 0.0017 − 0.07 − 0.017
Diarrhoea − 0.18 0.02 < 0.0001 − 0.22 − 0.14
Fatigue − 0.09 0.02 < 0.0001 − 0.12 − 0.05
Fluid retention − 0.07 0.01 < 0.0001 − 0.10 − 0.04
Nausea and vomiting − 0.21 0.02 < 0.0001 − 0.25 − 0.17
Reduced immunity − 0.14 0.02 < 0.0001 − 0.17 − 0.11

AE adverse event, CI confidence interval, GEE generalized estimating equation, SD standard deviation