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. 2019 Apr 11;10:755. doi: 10.3389/fmicb.2019.00755

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Copyright © 2019 Negretti, Clair, Talukdar, Gourley, Huynh, Adkins, Parker, Corneau and Konkel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The C. jejuni response to INT 407 and Caco-2 cells at 4 h is similar on the proteomic and transcriptomic level. Panels: (A) Protein profiles of C. jejuni co-cultured with human INT 407 and Caco-2 epithelial cells were compared. (B) RNA-Seq profiles of C. jejuni co-cultured with human INT 407 and Caco-2 epithelial cells were compared. (C) The proteins and genes from (A,B) that were significantly altered in both conditions (INT 407 and Caco-2, blue dots) were compared. Due to the high correlation between the INT 407 and Caco-2 transcript and protein profiles, the fold-change of the two host cell types was averaged.