Table 1.
Diversity estimates of microbial communities.
Mean ± SD | |||||
---|---|---|---|---|---|
Group | Tissue | Observed OTUs | Chao1 | Shannon | Simpson |
Control | Feces-start | 2225 ± 194.54 | 2889.58 ± 156.99 | 4.38 ± 0.27 | 0.94 ± 0.03 |
Feces-end | 2085.38 ± 318.54 | 2784.42 ± 381.64 | 4.04 ± 0.6 | 0.92 ± 0.03 | |
Ileum | 1101.75 ± 161.93 | 1611.59 ± 166.33 | 2.59 ± 0.89 | 0.77 ± 0.23 | |
ICLN | 436.88 ± 176.75 | 759.28 ± 270.57 | 3.55 ± 0.21 | 0.89 ± 0.04 | |
AB | Feces-start | 2365.13 ± 279.28 | 2998.69 ± 226.2 | 4.36 ± 0.58 | 0.93 ± 0.04 |
Feces-end | 1900 ± 213.57 | 2513.66 ± 260.61 | 3.84 ± 0.63 | 0.91 ± 0.05 | |
Ileum | 1165.75 ± 197.66 | 1716.42 ± 271.46 | 2.94 ± 0.57 | 0.84 ± 0.8 | |
ICLN | 361.5 ± 184.04 | 617.12 ± 291.39 | 3.52 ± 0.25 | 0.89 ± 0.05 | |
p-value | |||||
Ileum – Feces-start | < 0.0001 | < 0.0001 | < 0.0001 | 0.0017 | |
Ileum – Feces-end | < 0.0001 | < 0.0001 | < 0.0001 | 0.0055 | |
Ileum – ICLN | 0.0297 | 0.0009 | 0.0884 | 0.0203 | |
Feces-start – Feces-end | 0.0297 | 0.0164 | 0.0358 | 0.5315 | |
Feces-start – ICLN | < 0.0001 | < 0.0001 | < 0.0001 | 0.3156 | |
Feces-end – ICLN | < 0.0001 | 0.0343 | < 0.0001 | 0.5315 | |
Feces-end AB – Feces-end C | 0.2025 | 0.1422 | 0.4722 | 0.8638 | |
Ileum AB – Ileum C | 0.3638 | 0.2316 | 0.4482 | 0.3710 | |
ICLN AB – ICLN C | 0.8695 | 0.941 | 0.989 | 0.9707 | |
Absolute values represent data from the full dataset. p-values were calculated with the rarefied dataset. SD, Standard deviation; AB, Antibiotic group; C, Control group; ICLN, Ileocecal lymph node.