Figure 4.

Ergosterol quantification in native MSNP, PCN and PCN-MSNPs treated Candida strains showing reduction in ergosterol content by PCN-MSNP (8 µg mL⁻¹; 35.83 µM) as compared to standard, Miconazole. (A) C. albicans MTCC 227; (B) C. albicans MTCC 4748; (C) C. albicans MTCC 1637. (D) Reduction of ergosterol content by MSNPs at 500 µg mL⁻¹ (2.23 mM). There was no growth observed in any of the C. albicans strains tested at 500 µg mL⁻¹ (2.23 mM) of PCN or PCN-MSNPs. Untreated strains are used as control group (0 µg mL⁻¹). In Fig. 4(A–C), * indicates statistical significance (p = 0.0001, α = 0.05), by one way ANOVA.