Table 1.
Antifungal and fungicidal activity of native MSNPs, PCN and PCN-MSNPs.
| Yeast strains | PCN (µM) | PCN-MSNPs (µM) | MSNPs (µM) | Miconazole (µM) | |||
|---|---|---|---|---|---|---|---|
| MIC | MFC | MIC | MFC | MIC | MIC | MFC | |
| Candida albicans MTCC 183 | 69.8 | 139.76 | 17.4 | 34.9 | — | 9.3 | 18.7 |
| C. albicans MTCC 227 | 34.9 | 69.8 | 8.5 | 17.4 | — | 9.3 | 18.7 |
| C. albicans MTCC 1637 | 34.9 | 69.8 | 8.5 | 17.4 | — | 9.3 | 18.7 |
| C. albicans MTCC 3017 | 34.9 | 69.8 | 8.5 | 17.4 | — | 9.3 | 18.7 |
| C. albicans MTCC 3018 | 34.9 | 69.8 | 8.5 | 17.4 | — | 9.3 | 18.7 |
| C. albicans MTCC 4748 | 34.9 | 69.8 | 17.4 | 34.9 | — | 9.3 | 18.7 |
| C. albicans MTCC 7315 | 34.9 | 69.8 | 8.5 | 17.4 | — | 9.3 | 18.7 |
| C. parapsilosis MTCC 1744 | 34.9 | 69.8 | 17.4 | 34.9 | — | 9.3 | 18.7 |
| C. glabrata MTCC 3019 | 69.8 | 139.76 | 17.4 | 34.9 | — | 9.3 | 18.7 |
| C. krusei MTCC 3020 | 34.9 | 69.8 | 8.5 | 17.4 | — | 9.3 | 18.7 |
| Issatchenkia hanoiensis MTCC 4755 | 34.9 | 69.8 | 8.5 | 17.4 | — | 9.3 | 18.7 |
MIC: Minimum inhibitory concentration is the least concentration of test compound that could prevent visible growth of a microorganism, either bacteria or fungi, followed by incubation; MFC: Minimum fungicidal concentration is the least concentration of test compound that results in no growth of fungi at all or a growth with less than three colonies or 99% killing efficacy; PCN: Phenazine-1-carboxamide; MSNPs: Mesoporous silica nanoparticles; PCN-MSNPs: PCN-functionalized MSNPs; “—“: No activity.