Table 2.

Advantages/Disadvantages for MACI Transplantation Augmented With Autologous Bone Graft

Advantages	Disadvantages
Accurate restoration of the osteochondral unit given the compliant properties of the cancellous bone graft and MACI scaffold	2-stage procedure
Minimally invasive technique performed through a mini-arthrotomy or arthroscopic procedure	Cost of MACI scaffold
Ability to treat lesions that were once difficult to access, including tibial defects	Given the slower graft maturation process observed with MACI, it is important to counsel athletes that return to sports is unlikely to occur before 12 months.

MACI, matrix-induced autologous chondrocyte implantation.