Table 2. Comparisons of biochemical indexes between controls and cases.
| Variables | Control (n=520) | Cases (n=450) | t | P-value |
|---|---|---|---|---|
| BMI, kg/m2 | 26.9 ± 3.5 | 26.7 ± 3.6 | 0.876 | 0.381 |
| FBG, mg/dl | 5.6 ± 0.6 | 5.8 ± 0.7 | −4.791 | 0.000 |
| TC, mg/dl | 5.1 ± 0.9 | 5.0 ± 0.9 | 1.725 | 0.085 |
| TG, mg/dl | 1.8 ± 0.5 | 1.9 ± 0.5 | −3.106 | 0.002 |
| HDL-C, mg/dl | 1.1 ± 0.2 | 1.1 ± 0.2 | 0.000 | 0.999 |
| LDL-C, mg/dl | 3.2 ± 0.8 | 3.2 ± 0.9 | 1.904 | 0.057 |
| BUN, mg/dl | 4.7 ± 1.1 | 4.9 ± 1.2 | −2.707 | 0.007 |
| Creatinine, mg/dl | 67.6 ± 13.0 | 73.3 ± 12.7 | −6.883 | 0.000 |
| Uric acid, mg/dl | 350.9 ± 49.1 | 351.7 ± 46.4 | −0.259 | 0.795 |
| eGFR, ml/min | 72.3 ± 19.6 | 70.5 ± 21.0 | 1.380 | 0.168 |
| ALT, U/l | 21.9 ± 28.0 | 21.1 ± 21.2 | 0.496 | 0.620 |
| AST, U/l | 25.2 ± 10.8 | 24.5 ± 9.0 | 1.087 | 0.277 |
| RBC, ×1012/l | 4.9 ± 0.4 | 4.9 ± 0.6 | −309 | 0.757 |
| WBC, ×109/l | 6.5 ± 1.8 | 6.6 ± 1.7 | −0.885 | 0.376 |
| Hb, g/l | 138.5 ± 15.0 | 141.1 ± 14.1 | −2.661 | 0.008 |
| Plt, ×109/l | 246.2 ± 54.2 | 234.2 ± 57.5 | 1.454 | 0.147 |
| RDW, % | 12.6 ± 0.7 | 12.9 ± 0.9 | −5.831 | 0.000 |
| rs4646437 | 18.169 | 0.000 | ||
| GG | 303 (58.3%) | 246 (54.7%) | ||
| GA | 176 (33.8%) | 129 (28.7%) | ||
| AA | 41 (7.9%) | 75 (16.7%) |