Table 1.
Group | Description of the treatment | Number of mice (n) | Treadmill training | The total duration of the experiment (weeks) |
---|---|---|---|---|
C (Control) |
Saline (s.c.) and DMSO (i.p.) injections | 15 | NO | 10 |
CTT (Control + treadmill training) |
Saline (s.c.) and DMSO (i.p.) injections, 10 weeks of treadmill training | 11 | YES | 10 |
M (MPTP) |
MPTP (s.c.) and probenecid (i.p.) injections | 15 | NO | 10 |
METT (MPTP + early onset treadmill training) |
MPTP (s.c.) and probenecid (i.p.) injections 10 weeks of treadmill training started 1 week before the intoxication |
13 | YES | 10 |
MLTT (MPTP + late-onset treadmill training) |
MPTP (s.c.) and probenecid (i.p.) injections 10 weeks of treadmill training started immediately after the intoxication |
13 | YES | 16 |