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. 2019 Apr 3;2019:4927430. doi: 10.1155/2019/4927430

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Copyright © 2019 Tao Zhu et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Curcumin suppressed airway mucus secretion in OVA-induced chronic asthma. (a) After 75 days of OVA sensitization and challenge, mice were sacrificed and their right lower lungs were fixed. Then, tissue sections were stained with periodic acid-Schiff (PAS) staining. The figure demonstrates a representative view (×200) from each group; (b) mucus index was calculated as the percentage of the mucus-positive area of the whole bronchial epithelium; (c) qPCR was performed to measure MUC5AC mRNA expression in the lung; (d) western blotting was obtained to analyze MUC5AC protein expression in the lung. Each bar represents the mean ± SEM of 10 mice. ^∗P < 0.05 compared with control. ^#P < 0.05 compared with OVA. ^†P < 0.05 compared with OVA + Cur + shRNA-PPARγ.