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. 2019 Apr 4;6(4):e11981. doi: 10.2196/11981

Table 2.

Matched group comparisons at baseline.

Characteristics Original unmatched samples Matched samples
Comparison group (n=219) Active group (n=593) P value Comparison group (n=158) Active group (n=158) P value
Gender - female, n (%) 143 (65.3) 426 (71.8) .09 100 (63.3) 100 (63.3) 1.00
Age in years, mean (SD) 47.76 (11.94) 41.49 (13.06) <.001 45.86 (12.64) 44.03 (13.38) .21
Race - white, n (%) 212 (96.8) 537 (90.6) .01 151 (95.6) 149 (94.3) .80
GAD-7a, mean (SD) 10.40 (4.9) 11.24 (4.90) .03 10.46 (5.10) 10.91 (4.97) .43
SF-12b , mean (SD)c






Mental health 35.51 (10.18) 35.55 (9.90) .97 36.04 (10.27) 35.23 (9.44) .46

Physical health 37.04 (12.36) 42.61 (11.59) <.001 40.21 (11.93) 40.88 (12.27) .63
Medical complexity score 3.19 (2.44) 2.26 (2.07) <.001 2.75 (2.28) 2.73 (2.28) .94
High utilizer prior to studyd, n (%) 82 (37.44) 166 (27.99) .01 43 (27.22) 43 (27.22) 1.00
Any inpatient encounter in the past 6 months 30 (13.70) 60 (10.12) .19 14 (8.86) 20 (12.66) .36
Any emergency room visit in the past 6 months 53 (24.20) 116 (19.56) .18 34 (21.52) 31 (19.62) .78
Insurance type, n (%)

Medicare 44 (20.09) 48 (8.36) <.001 23 (14.56) 15 (9.49) .23

Medicaide 64 (29.22) 104 (18.12) .001 45 (28.48) 29 (18.35) .05

Commerciale 111 (50.68) 422 (73.52) <.001 90 (56.96) 114 (72.15) .01
Medications in past 6 months, n (%)

Other antidepressants 102 (46.6) 309 (52.11) .19 80 (50.6) 85 (53.8) .65

Tricyclic antidepressants 15 (6.9) 31 (5.23) .47 8 (5.1) 10 (6.3) .81

Benzodiazapines 57 (26.0) 122 (20.6) .12 42 (26.6) 42 (26.6) 1.00

Sleep medications 20 (9.1) 49 (8.3) .80 10 (6.3) 15 (9.5) .40

Stimulants 5 (2.3) 6 (1.0) .29 4 (2.5) 1 (0.6) .37

Mood stabilizers 46 (21.0) 56 (9.4) <.001 26 (16.5) 22 (14.0) .64

Buspirone 7 (3.2) 11 (1.9) .38 4 (2.5) 4 (2.5) 1.00

Atypical antipsychotics 11 (5.0) 26 (4.4) .84 4 (2.5) 7 (4.4) .54

Opioids 82 (37.4) 100 (16.9) <.001 31 (19.6) 33 (20.9) .89
ICD-10f codes, n (%)

Depression 91 (41.6) 230 (38.8) .526 55 (34.8) 70 (44.3) .11

Anxiety 92 (42.0) 248 (41.8) 1 61 (38.6) 73 (46.2) .21

Substance abuse 7 (3.2) 22 (3.7) .89 4 (2.5) 6 (3.8) .75

ADHDg 4 (1.8) 6 (1.0) .56 4 (2.5) 2 (1.3) .68
Medical conditionsh , n (%)

Hypertension 83 (37.9) 118 (19.9) <.001 54 (34.2) 44 (27.9) .27

Chronic GIi condition 66 (30.1) 131 (22.1) .02 43 (27.2) 45 (28.5) .90

Hyperlipidemia 60 (27.4) 93 (15.7) <.001 39 (24.7) 38 (24.1) 1.00

Obesity 48 (21.9) 91 (15.4) .04 28 (17.7) 28 (17.7) 1.00

Asthma 45 (20.6) 71 (12.0) .003 27 (17.1) 21 (13.3) .43

Diabetesb 44 (20.1) 41 (6.9) <.001 28 (17.7) 14 (8.9) .03

Chronic pain 35 (16.0) 83 (14.00) .55 19 (12.0) 23 (14.6) .62

Arthritis 37 (16.9) 54 (9.1) .003 22 (13.9) 15 (9.5) .29

aGAD-7: Generalized Anxiety Disorder-7.

bSF-12: Short Form Health Survey.

cFor the original unmatched samples, n=216 in the comparison group and n=559 in the active group.

dDefined as four or more outpatient medical encounters in 6 months prior to study enrollment.

eP<.05; cells show mean (SD) for continuous variables or n (%) for categorical variables.

fICD-10: International Statistical Classification of Diseases and Related Health Problems, 10th revision.

gADHD: attention-deficit hyperactivity disorder.

hReporting only those medical conditions with at least 10% prevalence.

iGI: gastrointestinal.