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. 2019 Mar 15;24(6):1037. doi: 10.3390/molecules24061037

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Scheme 1 — Synthetic route for obtaining compounds 6–10. Reagents and conditions: (i) POCl₃/DMF, CHCl₃, 0 °C to rt, then reflux; (ii) CH₃OH, piperidine; (iii) CH₃OH, HCl.