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. 2019 Mar 21;20(6):1438. doi: 10.3390/ijms20061438

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Compound 6g reduced the potentiation of GABA-induced Cl⁻ currents by CGS 9895 (2-p-methoxyphenylpyrazolo[4,3-c]quinolin-3-(5H)-one) in Xenopus oocytes expressing recombinant α1β2 GABA_A receptors. Data are expressed as the percentage potentiation of the response induced by GABA at EC_5–10 values, and are the mean ± SEM of values obtained from three to six oocytes.