Skip to main content
. 2019 Mar 25;11(3):700. doi: 10.3390/nu11030700

Figure 1.

Figure 1

Curcumin upregulated CISD2 expression in aged mice in vivo. (A,B) In vivo mouse model of aging. Results of CISD2 mRNA expression in the brains (A) and spinal cords (B) of mice at P2, 8, 25 and 104 weeks (n = 4 in each group). Curcumin enhanced CISD2 expression in a long-term culture of neural cells in vitro. Results of mRNA expression of CISD2 (C), iNOS (D), and RANTES (E) in the neural cells of mice with or without 1 μM curcumin treatment at 7 DIV and 35 DIV. Vertical bars indicate the mean ± (standard error of the mean (SEM)) of mRNA expression (n = 3). * p < 0.05, ** p < 0.01, and *** p < 0.001 indicate differences of statistical significance.