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. 2019 Mar 25;20(6):1492. doi: 10.3390/ijms20061492

Figure 6.

Figure 6

KRX-C7 improve insulin signaling in db/db mice. (A) Effects of KRX-C7 chronic infusion in the femoral quadriceps of db/db mice on insulin induced phospho-IRS1. (B) Effects of KRX-C7 chronic infusion in the femoral quadriceps of db/db mice on insulin induced Phospho-Ser473AKT. (C) Effects of KRX-C7 chronic infusion in the femoral quadriceps of db/db mice on insulin induced Phosphotyrosine 42/44 ERK. (D) Effects of KRX-C7 chronic infusion in the femoral quadriceps of db/db mice on insulin induced Phospho-Ser272-AMPK. For all graphs, densitometric analysis is expressed after normalization for appropriate control protein. Data points represent the mean ± SEM of three independent experiments. * p < 0.05 vs. Ins−; # p < 0.05 vs. Ins+.