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. 2019 Mar 22;20(6):1468. doi: 10.3390/ijms20061468

Figure 2.

Figure 2

CAPE treatment reverses vascular remodeling in MCT-induced PAH rats. (A) Representative images of media hypertrophy in lung sections from the rats described in (A). Lung sections were stained for Elastic van Gieson (EvG). High magnification of images derived from the blocks is further displayed. Scale bars, 50 μm. (B,C) The degree of vascular remodeling was evaluated by the pulmonary arterial wall thickness and the ratio of media thickness to lumen diameter using Image J analysis software. Values are means ± SEM. *** p < 0.01 vs. PBS group; ### p < 0.01 vs. MCT group. N = 10 independent images of arteries per group from five animals.