Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Mar 26;20(6):1504. doi: 10.3390/ijms20061504

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

The effect of SIN-1 treatment on 3-nitrotyrosine formation in B0AT1 protein. Immunoprecipitated B0AT1 protein from SIN-1-treated IEC-18 cells showed an increased level of 3-nitrotyrisine compared to immunoprecipitated B0AT1 protein from control cells. Densitometric analysis showed that the 3-nitrotyrosine formation was significantly increased in B0AT1 immunoprecipitated from SIN-1-treated IEC-18 cells. These studies indicated that OONO modifies tyrosine residues of B0AT1 and thus inhibits its trafficking to the BBM and subsequently its transport activity in IEC-18 cells.