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Anti-collagenase activity of silymarin and flavonolignans. Silybin (SB), dehydrosilybin (DHSB), isosilybin (ISB), silydianin (SD), silychristin (SC), silymarin (SM), 1,10-phenantroline (1,10-Ph). 1,10-Ph is a specific inhibitor of collagenase. Data are expressed as mean ± SEM from four independent experiments carried out in triplicate. # Significantly different from 1,10-Ph as the standard inhibitor at p = 0.05; * significantly different from silymarin at p = 0.05.
