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. 2019 Mar 7;11(3):572. doi: 10.3390/nu11030572

Figure 3.

Figure 3

Depressive-like behaviour in HSD and HFD groups. (A) Body weight of offspring after i.p. imipramine (30 mg/kg) administration 40 min prior to test session. (B) Forced swim test was used to determine swimming, climbing, and immobility events/5 min of male and female rats, as described in Materials and Methods. We video-recorded swimming, climbing, and immobility activities and evaluated each activity as an event which represents a count. Total swimming, climbing or immobility counts/5 min were quantified as shown as mean ± SD. (C,D) Forced swim test of standard chow diet (n = 7), HSD (n = 8), and HFD (n = 7) subjects. Imipramine (30 mg/Kg) administration to standard chow diet (n = 7), HSD (n = 8), and HFD (n = 5) groups was performed as described. Each count was evaluated during 5 min test. Graphs show mean ± SD. Statistical significance used a Kruskal–Wallis test, followed by a Dunn’s Multiple Comparison Test. * p < 0.05, ** p < 0.01, *** p < 0.001.