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. 2001 Nov 20;98(25):14487–14492. doi: 10.1073/pnas.251304398

Figure 1.

Figure 1

The Wnt pathway is required for tracheal development. Lateral views of embryos at late stages of embryogenesis stained with mAb2A12 to highlight the lumen of the tracheae. In all of the figures, anterior is to the left and dorsal is above. (A) Wild-type embryo. DT, dorsal trunk (arrow); VB, visceral branch (arrowhead). (B) fz−fz2− germ-line clones. The DT is completely missing apart from minute vestiges of DT material found in the posterior part. (C) wg−, a substantial amount of DT is formed (arrow). (D) Df(2L)RF, a similar phenotype to wg− is observed (arrow points to DT). (E) Ectopic expression of wg in all tracheal cells—note hypertrophy of DT (arrow). (F) Ectopic expression of DWnt2 in all tracheal cells—note hypertrophy of DT (arrow).