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. 2019 Mar 25;11(3):141. doi: 10.3390/pharmaceutics11030141

Figure 9.

Figure 9

Neutropenic study: The graph representing neutrophil count until 14 days after the administration of CBZ micellar solution, CBZ NPs, and CBZ liposomes at 2.5 mg/kg dose in female Sprague–Dawley (SD) rats in comparison with saline control. The neutropenic effect in animals showed that there was a drastic reduction in neutrophil count (0.1025 × 109/L) in animals administered with CBZ micellar solution on the fourth day. A depletion in neutrophil count was less observed in animals administered with CBZ liposomes (1.6725 × 109/L) and CBZ NPs (1.1 × 109/L) in comparison to CBZ micellar solution and saline control (2.635 × 109/L).