Table 1.
Hematological screening for different formulations of CBZ on the fourth day (data as mean ± SE, n = 5).
Blood Parameters | Unit | Control | Micellar Solution | NPs | Liposomes |
---|---|---|---|---|---|
WBCP | ×103 cells/µL | 14.67 ± 1.02 | 14.22 ± 1.43 | 14.57 ± 1.14 | 14.12 ± 3.11 |
WBCB | ×103 cells/µL | 15.09 ± 1.18 | 14.65 ± 3.21 | 15.32 ± 1.51 | 14.94 ± 2.17 |
RBC | ×106 cells/µL | 8.85 ± 0.95 | 6.82 ± 0.36 | 7.46 ± 2.04 | 8.12 ± 1.02 |
Neut | ×109 cells/L | 2.63 ± 0.232 | 0.1025 ± 0.65 | 1.1053 ± 0.48 | 1.6725 ±1.02 |
HGB | g/dL | 111.24 ± 3.27 | 10.30 ± 3.71 | 10.57 ± 1.27 | 11.07 ± 3.20 |
HCT | % | 443.9 ± 1.12 | 40.9 ± 2.62 | 41.1 ± 1.22 | 43.1 ± 1.26 |
MCV | fL | 557.81 ± 3.16 | 58.21 ± 1.17 | 56.43 ± 1.04 | 57.68 ± 1.02 |
MCH | Pg | 114.12 ± 1.24 | 13.93 ± 2.12 | 14.23 ± 1.17 | 14.35 ± 1.32 |
MCHC | g/dL | 224.35 ± 0.95 | 23.24 ± 0.30 | 24.15 ± 2.05 | 24.29 ± 1.22 |
CHCM | g/dL | 235.1 ± 1.26 | 33.8 ± 2.45 | 33.7 ± 1.25 | 33.3 ± 1.55 |
RDW | % | 115.60 ± 3.13 | 14.75 ± 3.15 | 15.45 ± 2.07 | 16.45 ± 1.16 |
HDW | g/dL | 2.33 ± 0.54 | 2.14 ± 0.41 | 2.17 ± 0.32 | 2.14 ± 0.18 |
PLT | ×103 cells/µL | 192 ± 12.35 | 155 ± 22.02 | 178 ± 24.34 | 232 ± 14.56 |
MPV | fL | 314.12 ± 1.25 | 9.51 ± 3.12 | 9.83 ± 3.45 | 11.52 ± 5.23 |
WBCP—White blood cell count perox, WBCB—White blood cell count baso, HGB—Hemoglobin, HCT—Hematocrit, MCV—Mean corpuscular volume, MCH—Mean corpuscular hemoglobin, MCHC—Mean corpuscular hemoglobin concentration, CHCM—Cell hemoglobin concentration mean, RDW—Red cell distribution width, HDW—Hemoglobin distribution width, PLT—Platelets, MPV—Mean platelet volume.