Table 5.

Combined analysis of PNPLA3 and MBOAT7 genotypes.

Fibrosis
rs738409 (PNPLA3)	rs641738 (MBOAT7)	Cases (%)	Controls (%)	aOR (95% CI)	p
CC	CC	23 (31.51)	87 (31.52)	0.99 (0.57–1.741)	1.00
CC	TC+TT	50 (68.49)	189 (68.48)
GC+GG	CC	18 (32.73)	43 (34.40)	0.93 (0.47–1.82)	0.83
GC+GG	TC+TT	37 (67.27)	82 (65.60)
Cirrhosis
rs738409 (PNPLA3)	rs641738 (MBOAT7)	Cases (%)	Controls (%)	aOR (95% CI)	p
CC	CC	57 (40.43)	87 (31.52)	1.47 (0.97–2.25)	0.07
CC	TC+TT	84 (59.57)	189 (68.48)
GC+GG	CC	32 (25.00)	43 (34.40)	0.64 (0.37–1.09)	0.10
GC+GG	TC+TT	96 (75.00)	82 (65.60)
Alcoholic Cirrhosis
rs738409 (PNPLA3)	rs641738 (MBOAT7)	Cases (%)	Controls (%)	aOR (95% CI)	p
CC	CC	31 (42.47)	87 (31.52)	1.60 (0.95–2.72)	0.08
CC	TC+TT	42 (57.53)	189 (68.48)
GC+GG	CC	18 (25.35)	43 (34.40)	0.65 (0.34–1.96)	0.19
GC+GG	TC+TT	53 (74.65)	82 (65.60)
HCV Induced Cirrhosis
rs738409 (PNPLA3)	rs641738 (MBOAT7)	Cases (%)	Controls (%)	aOR (95% CI)	p
CC	CC	18 (38.30)	87 (31.52)	1.35 (0.71–2.56)	0.36
CC	TC+TT	29 (61.70)	189 (68.48)
GC+GG	CC	8 (18.60)	43 (34.40)	0.44 (0.19–1.02)	0.02
GC+GG	TC+TT	35 (81.40)	82 (65.60)

OR—adjusted odds ratio; CI—confidence interval.