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. 2019 Mar 16;20(6):1328. doi: 10.3390/ijms20061328

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Arctigenin downregulates the arecoline-stimulated invasion and wound healing activities of BMF. Arecoline-treated BMF were subjected to (A) invasion or (B) wound healing assays in the presence of various concentrations of arctigenin. The experiments were repeated three times, and representative results are shown. The results are means ± SD. * p < 0.05 as compared with the non-arctigenin-treated group. # p < 0.05 as compared with the arecoline group. Magnification, ×100. The green dot line define the areas of wound healing cells.