Skip to main content
. 2019 Mar 21;12(6):949. doi: 10.3390/ma12060949

Figure 1.

Figure 1

Schematic of cHSA coating strategy for enhancing the stability and transfection efficiency of DNA origami. DNA origami was coated by cHSA via electrostatic interaction between the negatively charged DNA origami and positively charged cHSA. Plain DNA origami was degraded by DNase I and dissociated at acidic pH, whereas coated origami was found to be resistant to DNase I digestion and stable under the acidic condition. The coated DNA origami nanostructures could also be transfected to cells more efficiently.