Table 3.
Sample | Time | DLS | LD | Zeta Potential ± SD (mV) | pH ± SD | ||||
---|---|---|---|---|---|---|---|---|---|
MDD ± SD (nm) | PDI ± SD | Dv(90) (nm) | Particles < 500 nm (%) | Particles < 525 nm (%) | Particles > 5 µm (%) | ||||
A | 0 | 218.9 ± 3.5 | 0.06 ± 0.02 | 446 | 98.31 | 100 | 0 | −10.90 ± 0.26 | 6.33 ± 0.00 |
24 | 213.8 ± 2.9 | 0.07 ± 0.01 | 447 | 98.20 | 100 | 0 | −11.53 ± 0.51 | 6.34 ± 0.00 | |
A + Vit + TE | 0 | 209.9 ± 1.1 | 0.04 ± 0.02 | 453 | 97.70 | 100 | 0 | −12.73 ± 0.81 | 6.52 ± 0.00 |
24 | 213.6 ± 2.7 | 0.09 ± 0.02 | 453 | 97.75 | 100 | 0 | −13.57 ± 0.85 | 6.55 ± 0.01 | |
A + AMP + Vit + TE | 0 | 211.7 ± 2.3 | 0.08 ± 0.02 | 454 | 97.66 | 100 | 0 | −15.47 ± 0.60 | 7.05 ± 0.01 |
24 | 216.0 ± 3.5 | 0.08 ± 0.02 | 454 | 97.66 | 100 | 0 | −15.47 ± 0.70 | 6.95 ± 0.01 | |
B | 0 | 219.3 ± 1.7 | 0.07 ± 0.02 | 455 | 98.42 | 100 | 0 | −17.67 ± 1.14 | 6.43 ± 0.01 |
24 | 219.7 ± 1.6 | 0.08 ± 0.02 | 456 | 98.18 | 100 | 0 | −19.07 ± 0.71 | 6.43 ± 0.00 | |
B + Vit + TE | 0 | 215.4 ± 1.6 | 0.08 ± 0.01 | 457 | 98.74 | 100 | 0 | −20.40 ± 1.05 | 6.47 ± 0.01 |
24 | 218.9 ± 1.5 | 0.07 ± 0.03 | 455 | 98.18 | 100 | 0 | −20.63 ± 0.72 | 6.45 ± 0.00 | |
B + AMP + Vit + TE | 0 | 213.9 ± 1.4 | 0.09 ± 0.01 | 457 | 98.00 | 100 | 0 | −25.07 ± 0.60 | 7.00 ± 0.00 |
24 | 216.2 ± 0.6 | 0.08 ± 0.00 | 457 | 98.74 | 100 | 0 | −23.50 ± 1.28 | 6.88 ± 0.01 |
TPN: total parenteral nutrition; A: Lipofundin® MCT/LCT-containing TPN admixture without ampicillin; B: LIPIDem®-containing TPN admixture without ampicillin; A + VIT + TE, B + VIT + TE: TPN admixtures with vitamins and trace elements; A + AMP + VIT + TE, B + AMP + VIT + TE: TPN admixtures with ampicillin, vitamins, and trace elements; MDD: mean droplet diameter; PDI: polydispersity index; DLS: dynamic light scattering; LD: laser diffraction; Dv(90): 90% of the particles lies below the value; SD: standard deviation.