Table II.
Univariate and multivariate analyses of overall survival by the Cox proportional hazards model.
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| Clinicopathologic variables | HR | CI | P-value | HR | CI | P-value |
| Age | 1.062 | 0.991–1.138 | 0.087 | 1.060 | 0.978–1.150 | 0.157 |
| Tumor size | 0.661 | 0.221–1.974 | 0.458 | 2.733 | 0.544–13.726 | 0.222 |
| Tumor stage | 0.329 | 0.111–0.976 | 0.045 | 0.477 | 0.107–2.117 | 0.330 |
| Histologic grade | 0.837 | 0.262–2.672 | 0.763 | 1.122 | 0.402–3.131 | 0.826 |
| Node status | 0.773 | 0.365–1.639 | 0.502 | 0.556 | 0.171–1.800 | 0.327 |
| Histologic type | 2.878 | 1.282–6.464 | 0.010 | 2.328 | 0.543–9.972 | 0.255 |
| Molecular subtypes | 0.772 | 0.264–2.262 | 0.638 | 0.927 | 0.232–3.695 | 0.914 |
| Her2 status | 0.796 | 0.502–1.261 | 0.331 | 0.657 | 0.342–1.263 | 0.208 |
| CTC | 0.934 | 0.330–2.645 | 0.898 | 1.372 | 0.302–6.247 | 0.682 |
| Tif1γ status | 0.125 | 0.016–0.964 | 0.046 | 0.047 | 0.004–0.501 | 0.011 |
Significant P-values are denoted in bold font. HR, hazard ratio; CI, confidence interval; Her2, human epidermal growth factor receptor 2; CTC, circulating tumor cell; Tif1γ, transcription intermediary factor 1γ.