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. 2019 Mar 11;11(3):113. doi: 10.3390/pharmaceutics11030113

Table 1.

Common absorption permeation enhancers- application for nasal and pulmonary administration.

Class Enhancers Examples References
Surfactants Bile salts Sodium taurocholate [14,15]
Sodium deoxycholate sodium [16]
Glycodeoxycholat [17,18]
Surfactants Fatty acids and derivatives Palmitic acid [19]
Palmitoleic acid
Stearic acid
Oleyl alcohol
Oleic acid
Capric acid [20,21]
DHA, EPA [20]
Surfactants Phospholipids Dipalmitoyl phophatidyl choline, soybean lecithin, phosphatidylcholine [22,23]
Cationic polymers Polymers Chitosan and their derivatives [24,25,26]
Enzyme inhibitors Human neutrophil elastase inhibitor (ER143)
Cyclodextrins Beta-Cyclodextrin [27]
Tight junction modulators Claudine modulator Clostridium perfringens enterotoxin [28]
ZO modulator Zonula occludens toxin (ZOT) [29]