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. 2019 Mar 15;19(5):3696–3706. doi: 10.3892/mmr.2019.10045

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Copyright: © Tang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Epithelial-mesenchymal transition is induced by SDF-1 and inhibited by AMD3100 and DKK-1 in vitro. (A) WB demonstrated that the expression levels of α-SMA were increased and those of E-cadherin were reduced in the SDF-1 group, and these alterations were inhibited by AMD3100 and DKK-1, respectively. (B) Grayscale analysis of the WB. (C) Reverse transcription-quantitative polymerase chain reaction analysis revealed that the mRNA expression levels of α-SMA and E-cadherin corresponded to the results of the WB. (D) Quantitative analysis of the wound healing assay. (E) Representative images of the wound healing assay of the cells in the different groups at 0, 12 and 24 h post-scratching. *P<0.05 and **P<0.01 vs. control. SDF-1, stromal cell-derived factor 1; WB, western blotting.