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CLE-10-induced MDA-MB-231 cell death was mediated by autophagy. (a) Autophagy vesicles, autophagosomes, and autophagy lysosomes were observed in MDA-MB-231 cells after treatment with CLE-10. (b) MDA-MB-231 cells transfected with mRFP-GFP-LC3 adenovirus were detected with a confocal fluorescence microscopy. (c) The number of autophagosomes (yellow dots) and autolysosomes (red-only dots) in the control group and the CLE-10 group (** p < 0.01).
