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. 2019 Mar 23;20(6):1476. doi: 10.3390/ijms20061476

Table 2.

Conserved motifs of calcium binding protein CaMs, CMLs, CBLs and CPKs. In CaMs and CPKs D-x-D motifs are conserved at 14th and 16th position in each EF-hand.

EF-Hands CaMs CMLs CBLs CPKs
1st D-x-D, E-x2-E D-x3-D, F-x2-F V-F-H-P-N D-x-D, D-E-E-L, E-E-I, E-M-F
2nd D-x-D, D-F-x-E-F D-x3-D D & E D-x-D, D-E-E-L, E-x-E
3rd D-x-D D & E E-E-x-D, D-D-x2-E D-x-D, D-E-E-L, x-E-D
4th D-x-D D-x-D-x-D, F-x-E-F D-x-D, D-E-E-L, D/E