Table 3.
Pathogenic IgE binding peptide epitopes present in wheat identified using a mouse model.
| Protein | Pathogenic IgE Binding Peptide Epitopes |
|---|---|
| Salt-soluble protein | |
| LTP1 * | (1) QARSQSDRQS; (2) GIARGIHNLN |
| Alcohol-soluble proteins | |
| α-gliadin | (1) PLVQQQ; (2) QQQFPGQQQQ #; (3) YLQLQLP #; (4) YPQQQPQYLQ; (5) SFQQPQQQYP |
| ω2-gliadin | (1) FPTPQQQFPE; (2) QQSFPLQPQQ #; (3) QQLFPELQ |
| ω5-gliadin | (1) QQFPQQQ #; (2) QQLPQQQ #; (3) QQSPQQQ #; (4) QQEFPQQQ; (5) QQQFPQQEFP |
* LTP1 = Lipid transfer protein 1. #: Epitope is present in both the human and mouse model; Amino acids: Q = Glutamine; I = Isoleucine; P = Proline; F = Phenylalanine; G = Glycine; S = Serine; Y = Tyrosine; L = Leucine; E = Glutamic Acid; V = Valine; R =Arginine; N = Asparagine. Reference: [29].