Table 4.
Electrolyte balance, aldosterone and vasopressin blood level in Sprague Dawley rats maintained on either standard laboratory chow (TC), tryptophan-high chow (TH) or tryptophan-free chow (TF) for twee weeks.
| Group | TC | TH | TF |
|---|---|---|---|
| Electrolyte Intake with Food | |||
| Sodium (mmol/24 h) | 1.88 ± 0.05 | 2.09 ± 0.06 † | 1.33 ± 0.07 *,# |
| Potassium (mmol/24 h) | 4.37 ± 0.12 | 4.70 ± 0.13 † | 1.94 ± 0.09 *,# |
| Serum total Protein and Electrolytes | |||
| Total Protein (g/dL) | 5.28 ± 0.07 | 5.45 ± 0.03 † | 4.95 ± 0.15 # |
| Sodium (mmol/L) | 140.17 ± 1.30 | 141.00 ± 0.45 | 138.83 ± 1.62 |
| Potassium (mmol/L) | 4.82 ± 0.30 | 4.41 ± 0.14 | 4.40 ± 0.22 |
| Creatinine (mg/dL) | 0.78 ± 0.08 | 0.68 ± 0.03 | 0.72 ± 0.07 |
| Urea (mg/dL) | 54.17 ± 2.32 | 73.5 ± 1.52 *,† | 50.67± 3.77 # |
| Urinalysis | |||
| Specific gravity (g/L) | 1.036 ± 0.002 | 1.039 ± 0.002 † | 1.026 ± 0.004 # |
| Creatinine (mg/dL) | 61.69 ± 5.71 | 64.11 ± 3.77 † | 40.82 ± 6.21 *,# |
| Sodium (mmol/L) | 64.50 ± 6.66 | 110.63 ± 9.13 *,† | 62.75 ± 12.67 # |
| Sodium excretion (mmol/24 h) | 1.08 ± 0.09 | 1.78 ± 0.10 *,† | 1.23 ± 0.14 # |
| Potassium (mmol/L) | 247.58 ± 18.79 | 260.44 ± 16.33 † | 98.26 ± 17.30 *,# |
| Potassium excretion (mmol/24 h) | 4.14 ± 0.20 | 4.20 ± 0.12 † | 2.28 ± 0.16 *,# |
| Plasma Vasopressin an Aldosterone | |||
| Vasopressin (pg/mL) | 1500.2 ± 140.9 | 1304.6 ± 125.1 | 1171.1 ± 86.5 |
| Aldosterone (ng/mL) | 9.627 ± 1.620 | 8.706 ± 0.472 | 8.392 ± 0.649 |
* p < 0.05 vs. TC, # p < 0.05 vs. TH, † p < 0.05 vs. TF (by post-hoc Tukey’s test preceded by ANOVA). Means ± SE are presented.