Table 5.
Metabolic and water-electrolyte parameters at the beginning and at the end of experiments in rats treated with indole-3-propionic acid (I3P group) and rats treated with the vehicle (controls).
| Group | Controls | I3P | ||
|---|---|---|---|---|
| Before the treatment | At the end of treatment | Before the treatment | At the end of treatment | |
| Food intake (g) | 20.79 ± 0.49 | 18.77 ± 0.55 * | 21.11 ± 0.50 | 19.89 ± 0.71 |
| Caloric intake (kcal) | 57.08 ± 1.36 | 51.55 ± 1.50 * | 57.98 ± 1.37 | 54.61 ± 1.96 |
| Water intake (mL) | 28.86 ± 1.57 | 27.71 ± 2.17 | 29.26 ± 2.14 | 27.57 ± 2.77 |
| Urine output (mL) | 14.43 ± 1.21 | 15.86 ± 1.16 | 13.43 ± 1.07 | 14.29 ± 1.13 |
| Stool output (g) | 8.9 ± 0.72 | 8.01 ± 0.70 | 8.56 ± 0.52 | 7.43 ± 0.60 |
| Serum Electrolytes and Total Protein | ||||
| Sodium (mmol/L) | 143.14 ± 0.88 | 142.71 ± 1.06 | ||
| Potassium (mmol/L) | 4.47 ± 0.11 | 4.54 ± 0.05 | ||
| Creatinine (mg/dL) | 0.50 ± 0.02 | 0.54 ± 0.06 | ||
| Urea (mg/dL) | 51.57 ± 2.35 | 53.71 ± 3.56 | ||
| Total Protein (g/dL) | 5.30 ± 0.03 | 5.24 ± 0.07 | ||
| Urinalysis | ||||
| Specific gravity (g/L) | 1.039 ± 0.001 | 1.035 ± 0.001 * | 1.043 ± 0.003 | 1.038 ± 0.001 |
| Daily sodium excretion (mmol) | 1.07 ± 0.08 | 1.01 ± 0.04 | 0.89 ± 0.08 | 0.91 ± 0.04 |
| Daily potassium excretion (mmol) | 3.25 ± 0.17 | 3.11 ± 0.12 | 3.38 ± 0.09 | 3.03 ± 0.08 # |
* p < 0.05 vs. before the treatment in controls, # p < 0.05 vs. before the treatment in the I3P group. Means ± SE are presented.